2023
DOI: 10.1002/mame.202300246
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Oriented Porous Polymer Scaffolds in Tissue Engineering: A Comprehensive Review of Preparation Strategies and Applications

Tong Liu,
Yibo Wang,
Tairong Kuang

Abstract: The pursuit of effective therapeutic strategies for tissue damage has prompted extensive scholarly investigations worldwide. Tissue engineering has emerged as a prominent approach, particularly through the utilization of artificial scaffolds that closely resemble the natural extracellular matrix (ECM). These scaffolds exhibit multi‐scale topological structures and surface physicochemical properties, which significantly influence cellular behavior, thereby attracting considerable attention from numerous researc… Show more

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Cited by 4 publications
(3 citation statements)
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References 180 publications
(221 reference statements)
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“…94 This includes promoting cell adhesion, proliferation, and differentiation, all of which are essential processes in the intricate journey of nerve regeneration. 95 In conclusion, silk fibroin emerges as a promising natural biomaterial for peripheral nerve regeneration, offering a harmonious blend of biocompatibility, biodegradability, and mechanical strength. 96…”
Section: Silk Fibroin As a Natural Biomaterials For Peripheral Manage...mentioning
confidence: 99%
“…94 This includes promoting cell adhesion, proliferation, and differentiation, all of which are essential processes in the intricate journey of nerve regeneration. 95 In conclusion, silk fibroin emerges as a promising natural biomaterial for peripheral nerve regeneration, offering a harmonious blend of biocompatibility, biodegradability, and mechanical strength. 96…”
Section: Silk Fibroin As a Natural Biomaterials For Peripheral Manage...mentioning
confidence: 99%
“…BTE procedures typically utilise three-dimensional (3D) porous temporary support structures known as scaffolds made of various materials to neo-tissues during regeneration (Figure 1). These scaffolds assist stem cells in surviving, proliferating, migrating, and differentiating into various functional tissues [6]. They achieve this by providing a network of interconnected pores and struts that not only support mechanical loading but also enable efficient mass transport, allowing for the movement of nutrients and waste materials [7,8].…”
Section: Introductionmentioning
confidence: 99%
“…Computation 2024, 12, 74 2 of 31 differentiating into various functional tissues [6]. They achieve this by providing a network of interconnected pores and struts that not only support mechanical loading but also enable efficient mass transport, allowing for the movement of nutrients and waste materials [7,8].…”
Section: Introductionmentioning
confidence: 99%