1980
DOI: 10.1051/rnd:19800725
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Origin and utilization of volatile fatty acids in the rat

Abstract: Summary. The arteriovenous differences in the caecum of the rat have been compared for volatile fatty acids (VFA) Introduction.

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Cited by 63 publications
(18 citation statements)
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“…Minimum substrate utilization rate was calculated for untreated cortex as the product of the incorporation coefficient and plasma level. Plasma HCO 3 level was calculated from data in Table I; literature values were used for butyrate (Sarna et al, 1979;Rémésy et al, 1980) and acetate (Knowles et al, 1974;Buckley and Williamson, 1977). Calculated rates are minimal values because the integrated activity in plasma exceeds that of the true precursor pool in brain and there is some product loss due to decarboxylation reactions (see Results and Discussion (Sokoloff, 1986).…”
Section: Resultsmentioning
confidence: 99%
“…Minimum substrate utilization rate was calculated for untreated cortex as the product of the incorporation coefficient and plasma level. Plasma HCO 3 level was calculated from data in Table I; literature values were used for butyrate (Sarna et al, 1979;Rémésy et al, 1980) and acetate (Knowles et al, 1974;Buckley and Williamson, 1977). Calculated rates are minimal values because the integrated activity in plasma exceeds that of the true precursor pool in brain and there is some product loss due to decarboxylation reactions (see Results and Discussion (Sokoloff, 1986).…”
Section: Resultsmentioning
confidence: 99%
“…First-pass metabolism of propionate occurs almost exclusively in liver of rodents ( 45 ), where it is carboxylated and converted to the TCA cycle intermediate succinyl-CoA. Carbon isotope tracers of propionate have been used to assess relative rates of the hepatic TCA cycle in humans ( 46,47 ) and rodents (39)(40)(41).…”
Section: Relative Rates Of the Tca Cyclementioning
confidence: 99%
“…L'apport endogène continu de lactate par la bile, essentiellement, mais aussi par les sécré-tions pancréatique et intestinale (Le Bars et al, 1969 ;Vernay, 1986) Lankenau, 1954 ;Proto, 1973 ;Hôrnicke et al, 1976 ;Stephens, 1977 ;Catala et Vernay, 1974 ;Bonnafous et Raynaud, 1978). Chez le lapin, de même que chez les autres monogastriques : porc (Watanabe et Murai, 1968), rat (Mottaz et Worbe, 1972 ;Rémésy et Demigné, 1976) Vernay, 1974 ;McMillan, Edwards et Parker, 1975 ;Parker, 1976 Demigné, 1983). Pour les lapins porteurs de collier, nous n'avons pas de données bibliographiques, mais il a été montré, chez le ruminant (Dobson et Phillipson, 1956 ;Bensadoun, Paladines et Reid, 1962 ;Sellers, 1965).…”
unclassified
“…le chien (Kvietys et Granger, 1981) et le rat (Demigné et Rémésy, 1985) Lewis, 1957 ;Cook et Miller, 1965 ;Bergman et Wolff, 1971 ;Baird, Symonds et Ash, 1975). Chez le rat, le prélèvement hépatique concerne 50 % de l'acétate qui y transite et 85 à 95 % pour les deux autres AGV (Rémésy, Demigné et Chartier, 1980). Pour ce qui concerne le butyrate, il convient de rappeler que dans le sang porte du lapin, cet acide organique représente, en moyenne, 17 % de l'acidité volatile totale (Henning et Hird, 1972b ;Beauville, Raynaud et Vernay, 1974 ;McMillan, Edwards et Parker, 1975) alors que chez le ruminant (McClymont, 1951 ;Cook et Miller, 1965 ;Bergman et Wolff, 1971) et le porc (Friend, Nicholson et Cunningham, 1964) il n'est présent que pour 1,5 à 5 % et de 5 à 11 % chez le rat (Rémésy et Demigné, 1976 (Clauss, 1984(Clauss, , 1985Vernay et Marty, 1984 ;Vernay, Marty et Moatti, 1984).…”
unclassified
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