Origins of Cerebral Palsy

Naeye, Richard L.; Peters, Ellen C.; Bartholomew, Mary; Landis, RN Emily

doi:10.1097/00132582-199007000-00011

Cited by 31 publications

(50 citation statements)

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“…20 There are many risk factors for the occurrence of cerebral palsy, including maternal and antenatal factors such as prematurity, intrauterine infection, fetal coagulation disorders, multiple pregnancy, antepartum haemorrhage, breech presentation and chromosomal or congenital abnormalities. 5,6,8,9,14,[21][22][23][24][25] This is consistent with other findings showing that infants with cerebral palsy only occasionally have strong evidence of primary asphyxia at birth. 26 However, the fetus with established brain dysfunction or susceptibility factors may sometimes experience secondary hypoxia at birth, ie acute on chronic brain injury.…”

Section: Introductionsupporting

confidence: 92%

The Antenatal Causes of Cerebral Palsy – Genetic and Viral Associations

Gibson

MacLennan

Goldwater

et al. 2008

Fet. Matern. Med. Rev.

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Cerebral palsy is the most common neurological disorder in children. Epidemiological evidence suggests that antenatal origins are a major cause. Currently there is no antenatal test for cerebral palsy, no proven preventable measures in late pregnancy, and no known cure. Cerebral palsy affects not only the diagnosed child, but also their family and the community, requiring considerable social and financial resources to assist these children in their daily lives.

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Section: Introductionsupporting

confidence: 92%

The Antenatal Causes of Cerebral Palsy – Genetic and Viral Associations

Gibson

MacLennan

Goldwater

et al. 2008

Fet. Matern. Med. Rev.

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“…Grether et al, and others observed both were significantly associated with increased risk of developing CP. 10,15,19,20,21 Naeye et al and Nelson also reported that CNS infections had a high relative risk of 15.4 (95%) cl: (4.6-51.8) and 6.6-30.5 respectively. 2,3,19 In study renal failure, hypoglycemia and hypocalcemia found one (2.17%) in each, also reported increased association of these factors with cerebral palsy.…”

Section: Discussionmentioning

confidence: 98%

“…5 (10.86%) patients were having documentary evidence of hypoxic ischemic encephalopathy. 13,16,20 On analysis of various postnatal factors, neonatal seizures were single most common factor in 18 (39.13%) patients. Our findings were supported by a pioneer study conducted by Kapoor et al, Grether et al and Nelson.…”

Section: Discussionmentioning

confidence: 99%

A clinico-epidemiological study of cerebral palsy in western Rajasthan

Makwana¹,

Mourya²,

Mourya³

et al. 2017

Int J Contemp Pediatr

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INTRODUCTIONCerebral palsy (CP) is one of the leading causes of disability in children. Incidence of cerebral palsy varies from one to six per thousand live births. Besides handicapping a child, it causes considerable psychological and social trauma to the parents and financial burden to family and community. A cure for cerebral palsy (CP) has not yet been discovered, hence, a ABSTRACT Background: Cerebral palsy (CP) is one of the leading causes of disability in children. Incidence of cerebral palsy varies from one to six per thousand live births. Besides handicapping a child, it causes considerable psychological and social trauma to the parents and financial burden to family and community. A cure for cerebral palsy (CP) has not yet been discovered, hence, a need for primary prevention of disease. But unfortunately, the etiology of cerebral palsy is poorly understood thereby eluding a definitive prevention strategy. Methods: All cases of non-progressive neurological disorder in the age group of 0-9 years were enrolled in the present study. Thorough and complete Obstetric history including antenatal, natal and post-natal were recorded. Woodside scale is used for assessment of neurodevelopment and a complete anthropometric measurement, physical examination including detailed Central Nervous System and all neuroimaging and EEG were recorded. Severity of cerebral palsy was assessed according to Minear's classification. Statistical analysis was done by standard statistical methods. Results: Majority of patients were males (78.26%) as compared to females. The mean age of male patients was 2.04±1.53 years and females was 3.67±3.14 years. Spastic type of CP was most common (93.47%), followed by mixed (4.34%) and atonic (2.17%) type. Quadriplegic CP was the most common (76.75%), followed by diplegia (11.62%) amongst the spastic variety. Risk factors found are maternal pyrexia (17.39%), home vaginal delivery (58.70%), birth asphyxia (67.39%), Neonatal seizures (39.13%) other factors being icterus neonatorum (13.04%) and meconium aspiration syndrome (13.04%), ICH (10.86%), septicemia (8.69%) and renal failure (4.34%). Majority of the patients (78.26%) had class III and IV functional impairment. Cortical atrophy was the most commonly (71.73%) seen abnormality on neuroimaging with CT-scan. Epilepsy was present in 47.82% patients. Conclusions: Cerebral palsy along with its associated dysfunctions definitely disturbs the routine of children's life as well as family life. We have to go a long way before something definitive can be done for these children and their families.

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“…The majority of cases of CP are congenital, with problems during intrauterine development accounting for the majority of known causes (Naeye, Peters, Bartholomew, & Landis, 1989). Approximately 10% or less of cases are considered to be acquired.…”

Section: Causesmentioning

confidence: 99%

Common Pediatric Disabilities: Medical Aspects and Educational Implications

Tyler¹,

Colson²

2017

Exceptional

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The recent movement to include students with disabilities in general education classrooms poses a variety of challenges to school personnel. Many classrooms are now accommodating a wider variety of diversity, including a significant group of students with complex medical disorders (Smith & Luckasson, 1992;Stainback & Stainback, 1989). Successful inclusion of these students will depend on educators having a more comprehensive understanding of these disabilities and learning to collaborate with medical personnel.Advances in medical technology have changed the course for students in several ways. For example, it has dramatically increased the survival rate of at-risk neonates, as well as reduced the risk of life-threatening complications commonly associated with many disabilities (Brown, 1993;Goldson, 1993;Warshaw, 1992). In addition, major progress has been made in the ability to determine the etiology of many disorders, and associated research has provided insights into multidisciplinary treatments and interventions. As these medical advances continue, more and more children with disabilities will be entering the general education classroom. It is imperative, therefore, that educators possess current information and the skills necessary to collaborate effectively with medical and ancillary personnel.This article provides a brief overview of common pediatric disabilities and their implications for educators. An increased understanding of these disabilities will enable educators to explain the child's disability to parents and general education teachers, to make appropriate referrals for students who have not been identified, and to facilitate the assessment process and thereby achieve more appropriate programming.In this article each disability is defined, and current information about incidence and causes is summarized. Diagnosis is also discussed, including common characteristics. The complications section covers information about associated deficits in the cognitive, language, motor, behavioral, and academic areas. Finally, multidisciplinary intervention approaches are described and a list of resources for obtaining additional information is provided.

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Origins of Cerebral Palsy

Cited by 31 publications

References 0 publications

The Antenatal Causes of Cerebral Palsy – Genetic and Viral Associations

The Antenatal Causes of Cerebral Palsy – Genetic and Viral Associations

A clinico-epidemiological study of cerebral palsy in western Rajasthan

Common Pediatric Disabilities: Medical Aspects and Educational Implications

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