We have addressed the question of interfacial disorder in InAs/GaSb superlattices (SLs) grown by molecular-beam epitaxy using high-resolution transmission electron microscopy, Raman spectroscopy, X-ray di raction, and in-situ scanning tunnelling microscopy (STM). Our analysis indicates that InSblike interfaces have a roughness of 1 monolayer (ML), for a SL grown on a GaSb bu er layer. For GaAs-like interfaces, however, the interface roughness is found to be 2 ML when the SL is grown on a GaSb bu er. For SLs grown on an InAs bu er, the roughness of GaAs-like interfaces (3 ML) is also greater than that of InSb-like interfaces (2 ML). These results suggest two general observations. The ® rst is that GaAs-like interfaces are rougher than InSb-like interfaces. This di erence may be due to the high surface energy of GaAs compared with InSb or to di erences in surface kinetics. These observations are supported by in-situ STM results showing that the growth front surface morphology, for both GaSb and InAs layers, is rougher for GaAs-like interfaces than for InSb-like interfaces. We have also found that interface roughness is greater for an InAs/GaSb SL grown on an InAs bu er layer than for the same SL grown on a GaSb bu er layer. This di erence in interface roughness may arise because InAs SL layers are in tension when grown on a GaSb bu er layer, whereas GaSb SL layers are under compression when grown on an InAs bu er layer. §