Oro-Mandibular Dystonia in a Case of Multiple Sclerosis with Capsular Plaque

Rajabally, Yusuf A.; Farrell, Donald F.; Messios, N.

doi:10.1159/000069084

Cited by 13 publications

(8 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…54 OMD can be idiopathic (focal or as part of segmental or generalized dystonias), tardive, or secondary to other movement or neurological disorders. 55 A variant of OMD, Meige's syndrome, refers to a combination of upper and lower facial motor dysfunction, including blepharospasm and OMD. 54 In some cases, OMD includes lingual involvement, although isolated idiopathic, primary lingual dystonia has been reported.…”

Section: Cervical Dystoniamentioning

confidence: 99%

Botulinum Toxin in Movement Disorders

Papapetropoulos

Singer

2007

Semin Neurol

View full text Add to dashboard Cite

Botulinum toxin inhibits the vesicular release of acetylcholine in the neuromuscular junction, resulting in a transient, localized paralysis when small doses are injected. The successful use of serotypes A and B in conditions with muscle overactivity such as dystonia and spasticity has been well established. Apart from approved indications, treatment with botulinum toxin injections is attempted in a variety of new areas of neurology, including tremor, tics, and myoclonus. This article provides an update on the uses of botulinum toxin in the field of movement disorders and draws special attention to theoretical and practical treatment issues of primary and secondary dystonic disorders. Long-term experience with this agent suggests that it is an effective and safe treatment not only for approved indications but also for the increasing number of off-label indications. However, controlled studies for many conditions are lacking, and more clinical trials in many different areas are warranted.

show abstract

Section: Cervical Dystoniamentioning

confidence: 99%

Botulinum Toxin in Movement Disorders

Papapetropoulos

Singer

2007

Semin Neurol

View full text Add to dashboard Cite

show abstract

“…Generalized dystonia is described as an episode of unilateral upper limb flexion and lower limb extension with a potential to spread to the neck or face [ 14 , 15 , 16 ]. Focal forms include oromandibular dystonia [ 17 , 18 ], pharyngeal dystonia [ 19 ], and hand dystonia (writer’s cramp) [ 20 ]. These episodes are often precipitated by movement, hyperventilation, and physical or emotional stressors.…”

Section: Paroxysmal Symptoms Categoriesmentioning

confidence: 99%

Paroxysmal Symptoms in Multiple Sclerosis—A Review of the Literature

Freiha

Riachi

Chalah

et al. 2020

JCM

View full text Add to dashboard Cite

Paroxysmal symptoms are well-recognized manifestations of multiple sclerosis (MS). These are characterized by multiple, brief, sudden onset, and stereotyped episodes. They manifest as motor, sensory, visual, brainstem, and autonomic symptoms. When occurring in the setting of an established MS, the diagnosis is relatively straightforward. Conversely, the diagnosis is significantly more challenging when they occur as the initial manifestation of MS. The aim of this review is to summarize the various forms of paroxysmal symptoms reported in MS, with emphasis on the clinical features, radiological findings and treatment options.

show abstract

“…Acquired paroxysmal dystonia is frequently seen in the lesions involving the basal ganglia, extrapyramidal tract system, or thalamus. Other than typical localizations, sporadic cases exist involving demyelinated plaques in the cervical spinal cord, midbrain, medulla, internal capsule, and cerebral peduncle, even cases of MS not explainable by anatomical evidence have been reported (6,7). This paper suggests that in patients with acute paroxysmal dystonia, neuroimaging is often useful in excluding structural lesions.…”

mentioning

confidence: 90%