Orodispersible thin films: A Hodiernal Perspective in Drug Delivery System

Abstract

Undoubtedly that the ongoing epoch of pharmaceutical research has been focusing on the productive technological evolution of the drug delivery system so that the effectiveness appropriate to drug and patient’s sustainability can be strengthened. As determination and generation of present day chemical agents or substances are complex, expensive, and time-consuming procedure, so neoteric trends are reposition towards the drafting and advancing the inventive drug delivery systems for existing drugs. Among various pharmaceutical forms, orodispersible thin films have gained more interest from drug formulators to develop rapid drug-releasing formulations, especially for pediatrics and geriatrics patients. Furthermore, these strips have diverse merits over traditional fast-moving disintegrating tablets in consideration of schizophrenic and dysphasia patients. This convenience accommodates both the supremacy of marketing and enlarges patient compliance with this oral dosage form. Solvent casting and semi-solid casting methods are primary techniques that are used for the formulation of orodispersible thin films using a wide variety of hydrophilic polymers to achieve the desired biopharmaceutical attributes. In the current analysis article, recent improvements in the formulations of orodispersible films with their regulatory perspective are compiled.

A review on orodispersible drug delivery system

“…3). Controlled bottom drying is then used to dry the wet film; ideally, there are no external air currents or heat sources on the film's top surface [25].…”