Orofacial manifestations of Melkersson-Rosenthal syndrome

Zimmer, Wolfgang M.; Rogers, Roy S.; Reeve, Charles M.; Sheridan, Phillip J.

doi:10.1016/0030-4220(92)90354-s

Cited by 165 publications

(61 citation statements)

References 32 publications

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“…In 1992, Zimmer and al. reported a study that included 42 patients with MRS. Biopsy specimen was taken from swollen lips or facial tissue and 46% of patients had granulomatous inflammation, 36% had no specific inflammation, 11% had incidental findings, and 75 had no histological abnormalities [7]. Histological examination findings of our case reported mucositis.…”

Section: Discussionmentioning

confidence: 90%

Melkersson-Rosenthal Syndrome: A Rare Cause of Recurrent Facial Nerve Palsy and Acute Respiratory Distress Syndrome

Kosovalı

Yavuz

Yeşiler

et al. 2018

Case Reports in Neurological Medicine

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Melkersson-Rosenthal Syndrome (MRS) is a rare disease characterized by persistent or recurrent orofacial oedema, relapsing peripheral facial paralysis, and furrowed tongue. Pathologically, granulomatosis is responsible for oedema of face, labia, oral cavity, and facial nerve. We present a patient with MRS admitted to our hospital with acute respiratory distress syndrome (ARDS). 45-year-old woman was admitted to an emergency department with dyspnea and swelling on her hands and face. She was intubated because of ARDS and accepted to intensive care unit (ICU). After weaning from ventilatory support, peripheral facial paralysis was diagnosed and steroid treatment was added to her therapy. On dermatologic examination, oedema on her face, pustular lesions on her skin, and fissure on her tongue were detected. The patient informed us about her recurrent and spontaneous facial paralysis in previous years. According to her history and clinical findings, MRS was diagnosed.

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Section: Discussionmentioning

confidence: 90%

Melkersson-Rosenthal Syndrome: A Rare Cause of Recurrent Facial Nerve Palsy and Acute Respiratory Distress Syndrome

Kosovalı

Yavuz

Yeşiler

et al. 2018

Case Reports in Neurological Medicine

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“…The Melkersson-Rosenthal syndrome (MRS) is a rare granulomatous disease characterised by vesicles, lymphangiomas, facial paralysis and fissured tongue [3, 111, 112]. Tongue lesions were described in a large number of patients, arriving up to 75% in a study by Feng et al In the MRS there is an alteration of the microcirculation, in addiction to food intolerance determining malabsorption [113-116].…”

Section: Resultsmentioning

confidence: 99%

Diagnosis of Lingual Atrophic Conditions: Associations with Local and Systemic Factors. A Descriptive Review

Erriu¹,

Pili²,

Cadoni³

et al. 2016

TODENTJ

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Atrophic glossitis is a condition characterised by absence of filiform or fungiform papillae on the dorsal surface of the tongue. Consequently, the ordinary texture and appearance of the dorsal tongue, determined by papillary protrusion, turns into a soft and smooth aspect.Throughout the years, many factors, both local and systemic, have been associated with atrophic glossitis as the tongue is currently considered to be a mirror of general health. Moreover, various tongue conditions were wrongly diagnosed as atrophic glossitis. Oral involvement can conceal underlying systemic conditions and, in this perspective, the role of clinicians is fundamental.Early recognition of oral signs and symptoms, through a careful examination of oral anatomical structures, plays a crucial role in providing patients with a better prognosis.

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“…Labial swelling is often the first symptom and occurs mostly the upper lip (Kanerva et al, 2008). However, the lip swelling is often unilateral, firm, intermittent or persistent and, in the case of a cyst, it is soft, movable, pale, round and localized (Zimmer et al, 1992).…”

Section: Discussionmentioning

confidence: 99%