Oronasal Obstruction, Lung Volumes, and Arterial Oxygenation

Campbell, I.T.; Swift, A. C.

doi:10.1016/s0140-6736(88)90282-6

Cited by 47 publications

(23 citation statements)

References 24 publications

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“…18 This claim is strengthened by clinical research that indicates that normal rates of nasal resistance to expiration help to maintain lung volumes and may indirectly determine arterial oxygenation. 19 Elad et al 20 and Zhao…”

Section: Discussionmentioning

confidence: 99%

Assessment of Surgical Results in Patients With Empty Nose Syndrome Using the 25-Item Sino-Nasal Outcome Test Evaluation

Jiang

Wang

Chen

et al. 2014

JAMA Otolaryngol Head Neck Surg

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IMPORTANCE Empty nose syndrome (ENS) is an iatrogenic disorder, which severely affects the normal nasal breathing function. People affected by ENS may experience decreased productivity and lifestyle disruption. The 20-Item Sino-Nasal Outcome Test (SNOT-20) is a validated quality-of-life measurement and can be used to compare before and after intervention outcomes. OBJECTIVES To evaluate the effectiveness of the Medpor implant (Porex Surgical Inc) to improve the disease-specific quality of life in patients with ENS and to validate the 25-Item SNOT (SNOT-25) as an assessment tool in patients with ENS. DESIGN, SETTING, AND PARTICIPANTS We prospectively enrolled 24 patients from our hospital who received inferior turbinate reconstruction surgery after drug therapy failed to improve their symptoms. INTERVENTIONS All the patients underwent submucosal Medpor implant surgery to reconstruct their inferior turbinate. MAIN OUTCOMES AND MEASURES Patient assessments were based on the SNOT-25 questionnaire prior to surgery and at 3, 6, and 12 months after surgery. RESULTS The total scores of the SNOT-25 declined postoperatively, showing a significant difference at 3, 6, and 12 months after surgery compared with their initial visit (P = .045, P < .001, and P < .001, respectively). The 5 items most frequently reported by patients as important at their initial visit were "fatigue," "reduced concentration," "sadness," "dryness," and "nose is too open." The mean overall scores for these 5 important items also declined, showing statistically significant decreases compared with their initial visit (P < .05) and indicating that the items patients believed were important had improved. CONCLUSIONS AND RELEVANCE Medpor implant surgery in patients with ENS is associated with statistically significant improvements in disease-specific quality of life measures. The modified version of SNOT-20 Health Survey Scales, the SNOT-25,may be a useful measurement tool in patients with ENS.

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Section: Discussionmentioning

confidence: 99%

Assessment of Surgical Results in Patients With Empty Nose Syndrome Using the 25-Item Sino-Nasal Outcome Test Evaluation

Jiang

Wang

Chen

et al. 2014

JAMA Otolaryngol Head Neck Surg

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“…Conversely, FRC was observed to decrease after airflow was forced through the lower resistance oral passage following packing of the nasal passages to control haemorrhage. FRC was also noted to decrease following a decrease in nasal resistance resulting from surgery to relieve partial nasal obstruction [24].…”

Section: Pathophysiology Of Changes In Absolute Lung Volumes E Bancmentioning

confidence: 99%

“…There is, however, evidence that upper airways may indeed play a role in defining FRC in normal adults at rest. Residual volume (RV), FRC, and TLC have been reported to increase after 6-8 weeks of intradental wiring (an intervention which forces airflow through the higher resistance in the nares) [24]. Conversely, FRC was observed to decrease after airflow was forced through the lower resistance oral passage following packing of the nasal passages to control haemorrhage.…”

Section: Pathophysiology Of Changes In Absolute Lung Volumes E Bancmentioning

confidence: 99%

Pathophysiology of changes in absolute lung volumes

Bancalari

Clausen

1998

Eur Respir J

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Changes in absolute lung volumes are common in lung disease and result in significant impacts on gas exchange, respiratory muscle function, the sensation of dyspnoea, and limitations to maximal exercise. Though our knowledge regarding the magnitude and determinants of changes in lung volumes in health and disease has increased in the past 20 years, a number of important questions remain unanswered. Consideration of the limitations of specific methods for measuring lung volumes is essential when analysing published studies regarding absolute lung volumes in infants, children and adults. Though functional residual capacity is most commonly measured in children and adults with the subject awake and at rest, increasingly attention is being directed to making these measurements under clinically more relevant conditions (e.g. during exercise, sleep, anesthesia, or mechanical ventilation). The relationships between dynamic changes in functional residual capacity, flow limitation during tidal breaths, sensation of dyspnoea and exercise limitation are important to understand, and are the focus of current and future research. Improved understanding of these relationships may lead to improvements in therapy of patients with acute and chronic lung disease and are likely to be particularly important for evaluating the efficacy of and optimal patient selection for new modes of therapy, such as lung volume reduction surgery.

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“…Much of the work has been done by pulmonary physiologists in a nonclinical setting, and much of the work is quite old. 7,[9][10][11]19 This study has developed along a single line of research. These studies from our department first defined the physiologic parameters of the upper airway and then attempted to reproduce these parameters in patients with an end tracheostomy using a resistive heat moisture exchange device.…”

Section: Discussionmentioning

confidence: 99%