Oropharyngeal candidiasis among HIV seropositive patients in Chennai, South India: An evaluation of Polymerase chain reaction-Restriction Fragment Length polymorphism for speciation and Antifungal drug resistance

Jayachandran, Abirami Lakshmy; Katragadda, Radhika; Ravinder, Thyagarajan; Leela, K.V.; Kaliappan, Shanmugam; Chelliah, Amutha

doi:10.4103/jacm.jacm_23_16

Cited by 2 publications

(1 citation statement)

References 18 publications

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“…In the present study, there was higher preponderance among males, compared to females. The results were similar in a study conducted by Jayachandran, et al, 8 and Shymala et al, 9 which showed a higher preponderance among males. 16-45 age group was the most frequently affected, which was consistent with the finding reported from Vargas KG et al, 10 In this study most of cases fall into stage 4 category which was similar to study by S.R.…”

Section: Resultssupporting

confidence: 89%

Isolation and Speciation of Candida Species from Oral Thrush in HIV Seropositive Individuals from Tertiary Care Hospital

Nayaki¹

2021

Int.J.Curr.Microbiol.App.Sci

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Section: Resultssupporting

confidence: 89%

Isolation and Speciation of Candida Species from Oral Thrush in HIV Seropositive Individuals from Tertiary Care Hospital

Nayaki¹

2021

Int.J.Curr.Microbiol.App.Sci

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A systematic review on distribution and antifungal resistance pattern ofCandidaspecies in the Indian population

et al. 2021

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The emergence of antifungal drug resistance in Candida species has led to increased morbidity and mortality in immunocompromised patients. Understanding species distribution and antifungal drug resistance patterns is an essential step for novel drug development. A systematic review was performed addressing this challenge in India with keywords inclusive of ‘Candida’, ‘Antifungal Drug Resistance’, ‘Candidemia’, ‘Candidiasis’ and ‘India’. A total of 106 studies (January 1978-March 2020) from 20 Indian states were included. Of over 11,429 isolates, Candida albicans was the major species accounting for 37.95% of total isolates followed by C. tropicalis (29.40%), C. glabrata (11.68%) and C. parapsilosis (8.36%). Rates of antifungal resistance were highest in non-albicans Candida (NAC) species - C. haemuloni (47.16%), C. krusei (28.99%), C. lipolytica (28.89%) and C. glabrata (20.69%). Approximately 10.34% isolates of C. albicans were observed to be drug-resistant. Candida species were frequently resistant to certain azoles (ketoconazole-22.2%, miconazole–22.1% and fluconazole–21.8%). In conclusion, the present systematic review illustrates the overall distribution and antifungal resistance pattern of Candida species among the Indian population that could be helpful in the future for the formation of treatment recommendations for the region but also elsewhere.

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Oropharyngeal candidiasis among HIV seropositive patients in Chennai, South India: An evaluation of Polymerase chain reaction-Restriction Fragment Length polymorphism for speciation and Antifungal drug resistance

Cited by 2 publications

References 18 publications

Isolation and Speciation of Candida Species from Oral Thrush in HIV Seropositive Individuals from Tertiary Care Hospital

Isolation and Speciation of Candida Species from Oral Thrush in HIV Seropositive Individuals from Tertiary Care Hospital

A systematic review on distribution and antifungal resistance pattern ofCandidaspecies in the Indian population

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