1999
DOI: 10.1378/chest.115.6.1570
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Oropharyngeal Gram-negative Bacillary Carriage

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Cited by 48 publications
(31 citation statements)
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“…We are unaware of any studies that have documented colonization rates with gram-negative bacteria after the discharge of patients from intensive care units and general wards. The very low colonization rate upon admission in general ward patients is consistent with the results of a recent study demonstrating that healthy individuals rarely carry oropharyngeal gram-negative bacteria (32). Previously, the severity of underlying disease, mechanical ventilation, and the presence of nasogastric feeding tubes were associated with oropharyngeal gram-negative bacterial colonization (26,31,44).…”
Section: Discussionsupporting
confidence: 88%
“…We are unaware of any studies that have documented colonization rates with gram-negative bacteria after the discharge of patients from intensive care units and general wards. The very low colonization rate upon admission in general ward patients is consistent with the results of a recent study demonstrating that healthy individuals rarely carry oropharyngeal gram-negative bacteria (32). Previously, the severity of underlying disease, mechanical ventilation, and the presence of nasogastric feeding tubes were associated with oropharyngeal gram-negative bacterial colonization (26,31,44).…”
Section: Discussionsupporting
confidence: 88%
“…The oropharyngeal normal flora species isolated in children's cultures were Streptococcus from the group viridans, coagulase-negative Staphylococcus, and Moraxella spp, findings similar to those showed in epidemiological studies developed to evaluate the incidence of the oropharyngeal colonization by gram-negative aerobial bacilli (16) . Regarding the potentially pathogenic microorganisms seen in this study, a higher number of gram-negative species was isolated, the most important of which Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumanii.…”
Section: Discussionsupporting
confidence: 76%
“…Similarly, P. acnes phage PA6 was the most abundant phage in the filtered sample, yet appeared in extremely low abundance (<0.01%) in the chloroformed sample. P. acnes is ubiquitous in the healthy oral cavity, whereas Gramnegative bacteria such as E. coli are generally present in low abundance or not at all because they are rapidly cleared in healthy people (4,33,34). Abedon (35) demonstrated that phage with more abundant hosts tend to have shorter latent periods, i.e., a smaller lag time between adsorption and host lysis.…”
Section: Resultsmentioning
confidence: 99%
“…Microbiota can be trapped in the mucosa before adherence, inhibited by chemicals in saliva such as lactoferrin, or cleared by the host immune system (2, 33). Additionally, normal flora prevent the adherence and growth of transient microbiota by producing bacteriocins and manipulating the pH of oral microenvironments (2,33).…”
Section: Resultsmentioning
confidence: 99%