Oropharyngeal swallowing functions are impaired in patients with naive-achalasia

Sezgin, Baha; Eyigör, Sibel; Durusoy, Duygu; Ezgi, Karaoguz; Kirazlı, Tayfun; Bor, Serhat

doi:10.1007/s00405-020-05800-7

Cited by 5 publications

(1 citation statement)

References 26 publications

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“…These were cardiac arrhythmia, pneumonia, and disuse syndrome. Some recent reports have indicated that achalasia is associated with swallowing dysfunction 12 or frailty. 13 In this study, we defined "disuse syndrome" as extreme functional decline compared with the situation prior to POEM, such as swallowing dysfunction and inactivity during hospitalization requiring intensive rehabilitation.…”

Section: Assessment Of Safety and Efficacymentioning

confidence: 99%

Comparison of the safety and efficacy of peroral endoscopic myotomy between octogenarians and non‐octogenarians

Abe

Tanaka

Kawara³

et al. 2020

Digestive Endoscopy

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This study compared the safety and efficacy of peroral endoscopic myotomy for esophageal motility disorders between octogenarians and non-octogenarians. Methods: This retrospective observational study recruited 321 patients (28 octogenarians and 293 non-octogenarians) who underwent peroral endoscopic myotomy from two institutions. Clinical success (postoperative Eckardt score ≤ 3), technical success (completion of gastric and esophageal myotomy), and perioperative adverse events were compared between octogenarians and non-octogenarians. Perioperative adverse events were classified into major and minor adverse events based on the International Peroral Endoscopic Myotomy Survey criteria and were subdivided into technical and nontechnical adverse events according to the presence of a direct causal relationship with the procedure. Results: There were no significant differences in the rates of clinical success 1 year after treatment (100% vs. 97.3%, P = 0.64) and technical success (100% vs. 99.7%, P = 0.91) between octogenarians and non-octogenarians. Octogenarians had a higher incidence of perioperative adverse events (28.6% vs. 10.2%, P = 0.00097), particularly major adverse events (25.0% vs. 3.0%, P < 0.0001). There were no significant differences in the incidence of minor adverse events (7.1% vs. 7.9%, P = 0.67). Although there was no difference in the incidence of technical adverse events (10.7% vs. 9.2%, P = 0.74), octogenarians had a significantly higher incidence of non-technical adverse events (17.9% vs. 1.0%, P = 0.0002). Conclusions: There were no significant differences in shortterm clinical success and technical success between octogenarians and non-octogenarians. However, octogenarians showed a significantly higher incidence of perioperative adverse events, particularly in major adverse events and nontechnical adverse events. Peroral endoscopic myotomy for octogenarians should be carefully applied.

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Section: Assessment Of Safety and Efficacymentioning

confidence: 99%