Orthodontic treatment of mandibular incisor agenesis with Herbst appliance in a patient with Hanhart syndrome: A 12-year follow-up

Ribeiro, Tiago Turri de Castro; Laan, Helena Doneux Van der; Massaro, Camila; Lauris, Rita de Cássia Moura Carvalho; Kokitsu-Nakata, Nancy Mizue; Peixoto, Adriano Porto

doi:10.1016/j.ajodo.2021.01.035

Cited by 2 publications

(1 citation statement)

References 23 publications

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“…Nonsyndromic tooth agenesis is one of the most common dental problems; however, it can also be associated with various syndromes, including van der Woude syndrome, ectodermal dysplasia, oromandibular limb hypogenesis syndromes and hypoglossia-hypodactyly or Hanhart's syndrome. 29 , 30 Selective tooth agenesis is known to be associated with variants of PAX9, ectodysplasin A (EDA), MSX1, ectodysplasin A receptor (EDAR) associated death domain, wingless-type Mouse mammary tumor virus integration site family member 10A (WNT10A), bone morphogenetic protein 2 (BMP2), EDAR, axis inhibition protein 2 (AXIN2), DAN family BMP antagonist (GREM2) and gremlin 2. 7 , 27 , 29 , 31 , 32 Defects in MSX1 and PAX9 appear particularly sensitive to posterior teeth.…”

Section: Discussionmentioning

confidence: 99%

A Rare Incidence of Nonsyndromic Mandibular Incisor Agenesis in a Three-generation Family: Case Report and Literature Review

Duggal¹,

Selvaraj²,

Sennimalai³

et al. 2023

International Journal of Clinical Pediatric Dentistry

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A bstract Hypodontia is an inherited condition involving the absence of one to six teeth. The permanent dentition is the most frequently affected; however, it may also affect the primary dentition. A congenitally missing tooth (CMT) is the most common dental abnormality, with the missing mandibular second premolar, maxillary lateral incisor, maxillary second premolar, and mandibular central incisor accounting for 90% of CMT in hypodontia studies. The etiology of CMT has been attributed to environmental and genetic contributing factors, with the latter having a strong influence. It may occur in isolation or in association with syndromes. Congenitally missing mandibular incisor is more common in the Asian population and females. Depending on the number and location of missing teeth, hypodontia may be a considerable issue for the clinician since it may impact occlusal balance, mastication, speech, and esthetics and often requires a multidisciplinary approach. Missing mandibular incisors are of particular interest to orthodontists because of the possibility of mandibular retrognathism, the potential for the development of malocclusion, and difficulty in achieving a balanced occlusion. This case report describes the skeletal and dental features of a nonsyndromic familial occurrence of missing mandibular incisors in three generations. A comprehensive literature search was also performed to review the familial cases with missing mandibular incisors. How to cite this article Selvaraj M, Sennimalai K, Samrit VD, et al. A Rare Incidence of Nonsyndromic Mandibular Incisor Agenesis in a Three-generation Family: Case Report and Literature Review. Int J Clin Pediatr Dent 2023;16(2):388–395.

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Section: Discussionmentioning

confidence: 99%

A Rare Incidence of Nonsyndromic Mandibular Incisor Agenesis in a Three-generation Family: Case Report and Literature Review

Duggal¹,

Selvaraj²,

Sennimalai³

et al. 2023

International Journal of Clinical Pediatric Dentistry

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State of the Art in the Treatment of Congenital Agenesis With Implant‐Supported Prosthesis: A Comprehensive Multidisciplinary Management

Oliveira,

Pelegrine,

Barros-Filho

et al. 2024

Case Reports in Dentistry

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Congenital dental agenesis, particularly in younger adults, can have a profound impact on aesthetics and overall quality of life. The scientific literature offers various management strategies for this condition, with orthodontic movement and implant‐supported rehabilitation being central to treatment. However, achieving predictable and successful outcomes necessitates a comprehensive multidisciplinary approach. Such an approach integrates diverse professional perspectives to ensure accurate diagnosis, prognosis, and treatment planning, ultimately aiming to restore dental function and address aesthetic concerns effectively. In this case report, we present the successful rehabilitation of a young patient with congenital agenesis of the mandibular central incisors. The treatment strategy combined oral surgery (extraction of deciduous teeth and autogenous bone graft), orthodontic movement (opening spaces to allow implant installation), periodontics (connective tissue graft), implantology, and prosthetic planning. We detail the specific surgical approaches employed and discuss how their integration contributed to the overall success of the case. This multidisciplinary treatment approach not only restored dental function but also met the patient’s aesthetic expectations and enhanced the patient’s quality of life, highlighting the importance of a coordinated approach in managing complex dental conditions.

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Orthodontic treatment of mandibular incisor agenesis with Herbst appliance in a patient with Hanhart syndrome: A 12-year follow-up

Cited by 2 publications

References 23 publications

A Rare Incidence of Nonsyndromic Mandibular Incisor Agenesis in a Three-generation Family: Case Report and Literature Review

A Rare Incidence of Nonsyndromic Mandibular Incisor Agenesis in a Three-generation Family: Case Report and Literature Review

State of the Art in the Treatment of Congenital Agenesis With Implant‐Supported Prosthesis: A Comprehensive Multidisciplinary Management

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