During surgical procedures, the heat development of bone cutting can lead to thermal cell necrosis and secondary implant instability. Therefore, fundamental knowledge on heat development and temperature control is crucial. This paper investigates the basic principles of the machining of cortical bone in an orthogonal cutting process. Cutting forces, temperature elevation and chip formation were measured in real time for two different rake angles and six different cutting depths. A non-linear relationship between cutting depth and cutting forces as well as temperature elevation was found. A linear correlation between cutting forces and temperature elevation of both bone chip and workpiece was determined (R 2 = 0.8697) An increasing rake angle lowered cutting forces and temperature elevations significantly and was explained using a fracture mechanics approach. Additionally, a new method to calculate the fracture toughness of (quasi-)brittle materials from orthogonal cutting tests was introduced. Recent advances in numerical modeling of bone cutting have been summarized by Marco et al. [15] but there are only limited models for the cutting of brittle or quasi-brittle materials [16].However, compared to metals, cortical bone is a very different material with a quasi-brittle and not ductile behavior. It is anisotropic with osteons (∅ 200 µm)