In recent years, researchers focused their attention on the construction of nonlocal product states in multipartite quantum systems. This paper proposes a novel partitioning method for multipartite quantum systems, aiming to improve the operation efficiency. Firstly, we divide 2n subsystems into n parts two by two and implement orthogonality-preserving local measurement on the partitioned composite systems. Subsequently, based on the partitioning mode, nonlocal orthogonal product states in
(
C
3
)
⊗
6
and
(
C
4
)
⊗
6
are given. Finally, we construct nonlocal orthogonal product states in
(
C
d
)
⊗
2
n
and discuss the cases where d is odd and even. Our results demonstrate the phenomenon of nonlocality without entanglement in a 2n-partite system.