Orthopedic Implant-Associated and Central Venous Catheter-Associated Infections Caused by <i>Microbacterium</i> spp. in the Veterans Affairs Healthcare System from 2000 to 2020

Twardy, Brandon; Yasmin, Mohamad; Bej, Taissa; Wera, Glenn D.; Marshall, Steven H.; Rojas, Laura; Jump, Robin L.P.

doi:10.1089/sur.2021.133

Cited by 2 publications

(1 citation statement)

References 16 publications

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“…The infection route and pathogenetic mechanism in clinical patients are, however, not clear. Some studies believe that Microbacterium can cause catheter-related infection, internal fixation device infection [ 17 , 18 ] or endocarditis [ 19 ]. It can also cause nosocomial infection outbreaks [ 20 ] and form biofilms similar to Ralstonia .…”

Section: Discussionmentioning

confidence: 99%

Persistent bacteremia caused by Ralstonia pickettii and Microbacterium: a case report

Wang,

Song,

Liu

et al. 2024

BMC Infect Dis

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Background Ralstonia pickettii is a low virulent, gram-negative bacillus that is rarely associated with human infections and may cause bacteremia. Microbacterium species are gram-positive coryneforms that are generally considered as a contaminant in Gram staining of blood cultures, especially when the time to positivity is longer than 48 h. Both these bacterial species are emerging opportunistic pathogens that may occasionally cause serious infections and even life-threatening health conditions. Case presentation Here, we report the case of a patient with bacteremia caused by both R. pickettii and Microbacterium. We advocate for providers to order rapid antibiotic susceptibility testing, since our patient’s suffered two kinds of rare pathogens with the opposite of drug sensitivity results to imipenem. Conclusions Our case present a patient suffered septic shock caused by R. pickettii and Microbacterium. Improving the antibiotic management based on the result of antimicrobial susceptibility tests is the key of successful treatment.

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Section: Discussionmentioning

confidence: 99%

Persistent bacteremia caused by Ralstonia pickettii and Microbacterium: a case report

Wang,

Song,

Liu

et al. 2024

BMC Infect Dis

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Coryneform Gram‐Positive Rods

Mattos‐Guaraldi,

Santos,

Vieira

2023

ClinMicroNow

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This chapter presents Coryneform bacteria comprising aerobically or facultatively anaerobically growing, asporogenous, non‐acid fast Gram‐positive rods with irregular morphology. Establishing the clinical significance of coryneform bacteria can be difficult for caregivers and microbiologists. Corynebacterium spp. form the predominant group and include diphtheria toxin (DT)‐producing Corynebacterium diphtheriae , the causative agent of classic diphtheria, which was once a major cause of illness and death among children. Laboratory procedures for identification of Corynebacterium spp. and other coryneform bacteria include collection and transport of clinical samples, isolation practices, culture conditions, phenotypic and molecular assays, as well as antimicrobial susceptibility testing. Molecular techniques have been increasingly used in microbiology laboratories for the identification of Corynebacterium species and other coryneform bacteria. Detection of antibodies directed against DT is the only established serologic test for coryneform bacteria.

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Orthopedic Implant-Associated and Central Venous Catheter-Associated Infections Caused by Microbacterium spp. in the Veterans Affairs Healthcare System from 2000 to 2020

Cited by 2 publications

References 16 publications

Persistent bacteremia caused by Ralstonia pickettii and Microbacterium: a case report

Persistent bacteremia caused by Ralstonia pickettii and Microbacterium: a case report

Coryneform Gram‐Positive Rods

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