Orthopedic infections due to Trichosporon species: Case series and literature review

Abstract

Reports of orthopedic fungal infections caused by Trichosporon species are extremely scarce, thus we aimed to describe a case series and review the cases published in the literature. Patients were retrospectively included if a previous culture of bone, joint or soft tissues had resulted positive for Trichosporon species, along with a clinical diagnosis of an orthopedic infection. Eight patients were included, with diverse orthopedic conditions, most of them being cases of osteomyelitis. The main isolated species was Trichosporon asahii. All patients were treated with antifungals, mainly voriconazole, and surgical management, resulting in high rates of clinical improvement and a low associated mortality.