Orthostatic Intolerance and Gastrointestinal Motility in Adolescents With Nausea and Abdominal Pain

Abstract

Although altered gastric emptying and postural tachycardia are common in a referral population of adolescents with nausea and/or abdominal discomfort, the clinical presentation was not predictive of test results. Furthermore, delayed gastric emptying was not correlated with the current definition of postural tachycardia.

Antroduodenal Manometry Is Abnormal in Children Presenting With Orthostatic Intolerance and Gastrointestinal Symptoms

“…In a subsequent study that used electrogastrography to assess changes in the fundus and antral regions of the stomach, electrical activity was normal in the supine position, but became abnormal in the upright position. (13) These measurements suggested that electrical activity increased in the fundal region (tachygastria) and slowed in the antrum (bradygastria).Previous studies have shown that gastric emptying time correlated poorly with symptoms of OI and heart rate response to TTT (8,. 11) Our data confirms the poor reliability of GES and its correlation with abnormal motility.…”

Nausea in Children With Functional Abdominal Pain Predicts Poor Health Outcomes in Young Adulthood

“…Abdominal pain and recurrent nausea are common among children with POTS and it is known to co-exist with FGIDs. 25,26 We cannot rule out the possibility that some children may have had POTS and not FAP complicated by nausea. We also did not perform gastric emptying studies in all participants to rule out gastroparesis.…”

The utility of Valsalva maneuver in the diagnoses of orthostatic disorders

“…Patterning of linked to OI hemodynamic responses may enhance qualitative VM evaluation and thus improve the diagnosis of various autonomic disorders characterized by orthostasis. Improved VM assessment would be clinically beneficial, as OI can be a substantial cause of morbidity (2,11,21,23,27). Therefore, the present study's aim was to clarify the contribution of the VM to the diagnosis of OI.…”