Orthotopic liver transplantation in alcoholic liver cirrhosis

Romano, Domenico; Jiménez, Carlos; Rodríguez, Fernando San Juan; Loinaz, Carmelo; Colina, F; Ureña, Miguel Ángel García; García, Ignacio; Moreno, Enrique

doi:10.1016/s0041-1345(99)00432-7

Cited by 17 publications

(11 citation statements)

References 11 publications

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“…14,15,27 Other studies supported an association between HCV infection and depression. These studies found that patients with HCV infection were more likely to have psychiatric disorders; depression was the most frequent and clinically important diagnosis.…”

Section: Discussionmentioning

confidence: 97%

Predictors of psychiatric disorders in liver transplantation candidates: Logistic regression models

Rocca

2003

Liver Transplantation

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This study has two goals. The first goal is to assess the prevalence of psychiatric disorders in orthotopic liver transplantation (OLT) candidates by means of standardized procedures because there has been little research concerning psychiatric problems of potential OLT candidates using standardized instruments. The second goal focuses on identifying predictors of these psychiatric disorders. One hundred sixty-five elective OLT candidates were assessed by our unit. O rthotopic liver transplantation (OLT) is an accepted standard of care for end-stage liver disease. The pre-OLT period is marked by declining physical function, adjustment-related anxiety and depression, and development of organic brain deficits. [1][2][3][4] Although several psychiatric follow-up studies are available for recipients and donors after OLT, [5][6][7] there are few studies concerning the psychiatric status of potential OLT candidates before OLT. There is heterogeneity in the results of these studies, and the findings need to be interpreted with caution because psychiatric diagnoses were determined by means of psychometric scales and only in few cases by a comprehensive clinical interview. 7,[8][9][10][11][12] Reported prevalence rates of psychiatric disorders among OLT candidates vary from 15% to 50%. [8][9][10][11][12] Another recent study describing psychological characteristics of a large sample of OLT candidates reports that more than half the patients presented at least mild levels of depression, and more than one third were affected by clinically elevated levels of anxiety, suggesting a greater incidence of depression and anxiety than previously reported. 13

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Section: Discussionmentioning

confidence: 97%

Predictors of psychiatric disorders in liver transplantation candidates: Logistic regression models

Rocca

2003

Liver Transplantation

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“…What factors account for the phenomena described by the specifiers? [5][6][7] How can we use them clinically? Clinical prognosis is judged from a complex combination of observable phenomena, not an arbitrary 6-month rule that is indefensible but used by transplant programs because of its simplicity and its assuaging properties regarding transplant propriety.…”

mentioning

confidence: 99%

Liver transplantation for alcoholic liver disease: Bias, beliefs, 6-month rule, and relapse—but where are the data?

Beresford

Everson

2000

Liver Transpl

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“…Similar survival rates have been reported for ALD patients in the US after LT: 92% at 1 year, 86% at 3 and 5 years and 76% at 9 years (Bhagat et al, 2009). It has been shown that patients with ALD had similar patient and graft survival rates, if not better in some cases, compared to those of patients undergoing LT for other indications (Dumortier et al, 2007;Mutimer et al, 2006;Romano et al, 1999). In a "perfect" world patients would have a single aetiology for their end-stage liver disease, unfortunately in the real world patients may undergo LT for ALD in the presence of other comorbidities, which can significantly affect the result.…”

Section: Outcome Of Lt For Ald and Ethical Issues 31 Outcome Of Lt Fmentioning

confidence: 99%

The Role of Liver Transplantation in theTreatment of Alcoholic Liver Disease

Tsoulfas¹,

Agorastou²

2012

Trends in Alcoholic Liver Disease Research - Clinical and Scientific Aspects

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Orthotopic liver transplantation in alcoholic liver cirrhosis

Cited by 17 publications

References 11 publications

Predictors of psychiatric disorders in liver transplantation candidates: Logistic regression models

Predictors of psychiatric disorders in liver transplantation candidates: Logistic regression models

Liver transplantation for alcoholic liver disease: Bias, beliefs, 6-month rule, and relapse—but where are the data?

The Role of Liver Transplantation in theTreatment of Alcoholic Liver Disease

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