Orthotopic Liver Transplantation in an Adult With Biliary Atresia, Situs Inversus, and Inferior Cava Vein Absence: A Case Report

Soria, Nicolasa Fernández; Novoa, María Alejandra García; Polo, Jose Ignacio Rivas; Sellés, C. Fernández; Vázquez, María de los Ángeles; Milagros, M. Marini; Gutiérrez, Manuel Gómez

doi:10.1016/j.transproceed.2015.08.032

Cited by 6 publications

(1 citation statement)

References 5 publications

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“…Moreover, in most children, BA is accompanied by jaundice, which is a great threat to the child’s physical and mental health and quality of life[ 1 - 5 ]. Surgery is an important measure for the clinical treatment of BA, in which hepatojejunostomy is most commonly used[ 6 - 8 ]. However, approximately 60% of children still require liver transplantation before the age of 20 years, and portal hypertension, nutritional dysplasia, and liver cirrhosis have a large impact on the long-term survival rate[ 9 - 12 ].…”

Section: Introductionmentioning

confidence: 99%

Application of narrative nursing in the families of children with biliary atresia: A retrospective study

Zhang¹,

Meng²,

Wang³

et al. 2021

WJCC

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BACKGROUND Narrative nursing is an important clinical nursing intervention model. It is the practice of patient storytelling to share the essence of nursing. The current clinical intervention for biliary atresia (BA) mainly focuses on disease treatment and does not pay enough attention to the psychological state of family members. AIM To explore the application value of narrative nursing in the families of children with BA. METHODS Sixty-four family members of children with BA in our hospital from December 2017 to October 2020 were retrospectively included and were divided into a study group ( n = 32) and a control group ( n = 32). The control group was provided with routine nursing, while the study group was given narrative nursing on the basis of the control group. The scores of mood state (depression and anxiety), family members’ nursing ability, perceived stress, and nursing job satisfaction of the children’s families were calculated before and after the intervention. RESULTS Before intervention, there was no significant difference in the self-rating anxiety scale and self-rating depression scale scores between groups ( P > 0.05). After intervention, the self-rating anxiety scale and self-rating depression scale scores in the study group were lower than those in the control group (both P = 0.000). Before intervention, the study group adjusted life to meet care needs, evaluated family members and social resources, dealt with personal emotions, responded to needs, and provided assistance, and the adaptive care role scores were not significantly different from those in the control group ( P = 0.802, 0.819, 0.694, 0.796, and 0.686, respectively). After intervention, all scores were significantly lower in the study group than in the control group (all P < 0.0001). Before intervention, there was no significant difference in the child post-traumatic stress disorder symptom score (CPSS) score between groups ( P = 0.615). After intervention, the CPSS scores were significantly lower than those before intervention in both groups and lower in the study group than in the control group ( P < 0.0001). Nursing job satisfaction of the family members of the study group (93.75%) was higher than that of the control group (75.00%) ( P = 0.039). CONCLUSION Narrative nursing with family members of children with BA can effectively alleviate negative emotions, reduce perceptual pressure, and improve nursing ability. Additionally, family members are more satisfied with nursing work.

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Section: Introductionmentioning

confidence: 99%

Application of narrative nursing in the families of children with biliary atresia: A retrospective study

Zhang¹,

Meng²,

Wang³

et al. 2021

WJCC

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Establishment and characterization of an immortalized human hepatocyte line for the development of bioartificial liver system

et al. 2018

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For further research and application of Bioartificial liver systems (BAL), active proliferation capacity and full hepatic functionality of the biomaterials is mandatory. However, there are still no suitable cell lines meeting the requirements for an ideal cell source in BAL development that makes it necessary to explore other sources. Here, we constructed a new cell line derived from well-differentiated hepatocellular carcinoma tissues designated NHBL2. Immunol staining showed that NHBL2 possessed the capacity of synthesizing albumin and CYP2E1 and quantitative analysis showed that the albumin synthesis ability of NHBL2 was comparable to C3A while urea production was highly abundant of NHBL2 compared with that of C3A. Using gene expression microarray analysis, we found that the expression levels of a set of genes encoding Phase I and Phase II metabolizing enzymes as well as many others related to common bioconversion and metabolic processes were significantly higher in NHBL2 cell line than that in C3A. Moreover, functional optimization assay in Matrigel showed obvious improvements of liver-related function level and a low malignance of this cell line. These findings indicated that NHBL2 possessed relatively attractive and full hepatic functionality that might be a potential cell line for BAL development.

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Living-Donor Liver Transplantation for Budd-Chiari Syndrome: Case Series

Karaca

Yilmaz

Ferecov

et al. 2017

Transplantation Proceedings

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Orthotopic Liver Transplantation in an Adult With Biliary Atresia, Situs Inversus, and Inferior Cava Vein Absence: A Case Report

Cited by 6 publications

References 5 publications

Application of narrative nursing in the families of children with biliary atresia: A retrospective study

Application of narrative nursing in the families of children with biliary atresia: A retrospective study

Establishment and characterization of an immortalized human hepatocyte line for the development of bioartificial liver system

Living-Donor Liver Transplantation for Budd-Chiari Syndrome: Case Series

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