Orthotopic neobladder and subsequent renal transplantation

Nimeh, Toni; Ng, Christopher; Goldfarb, David A.; Klein, Eric A.

doi:10.1016/s0090-4295(02)01895-2

Cited by 4 publications

(1 citation statement)

References 2 publications

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“…Nevertheless, despite tried‐and‐true techniques and satisfactory functional results, few patients suffering from end‐stage renal disease have benefited from this type of diversion. In all, we found reports of 48 transplantations in adults with a continent pouch since 1989, with just four authors reporting more than two patients (Table ) …”

Section: Discussionmentioning

confidence: 97%

Long‐term kidney transplant survival in patients with continent urinary diversion

et al. 2017

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Section: Discussionmentioning

confidence: 97%

Long‐term kidney transplant survival in patients with continent urinary diversion

et al. 2017

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RETRACTED ARTICLE: Long-term results of standard procedures in urology: the ileal neobladder

et al. 2006

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Long-term results of standard procedures in urology: the ileal neobladder

et al. 2006

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Over the past 20 years orthotopic urinary reconstruction with the techniques developed at Ulm and Bern has become a widely accepted form of urinary diversion. So far, both centers together have performed more than 1,300 orthotopic bladder substitutions with an overall rate of neobladder formation in 58% of all cystectomized patients. Today, the absolute contraindications for this procedure are urinary stress incontinence, damaged rhabdosphincter, severely impaired renal and liver function, severe intestinal diseases or an oncologic situation requiring urethrectomy. In patients treated for transitional cell carcinoma of the bladder, the rate of urethral recurrence in both centers was 1.5 and 5%, respectively, and the rate of upper urinary tract recurrence was 2-3%. Local tumor recurrence usually did not affect neobladder function. The rate of outlet obstruction by local recurrence was 2%, that of gross hematuria 1%, and of entero-reservoir fistulas 1-2%. Daytime continence at 12 months was 92%, while nighttime continence was lower around 80%. Transient or permanent urinary retention was seen in 11-12% of male patients. In both series, long-term upper urinary tract safety was good. The risk of stenoses of the uretero-intestinal anastomosis with consecutive loss of renal function decreased with the introduction of non-refluxing implantation techniques. The rate of long-term metabolic complications remains low when adequate substitution with sodium bicarbonate is guaranteed in patients with impaired renal function. Patient selection and meticulous postoperative follow-up contributed to achieve good long-term results after cystectomy and orthotopic ileal neobladder substitution of the two large series of patients from the Universities of Ulm and Bern.

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Orthotopic neobladder and subsequent renal transplantation

Cited by 4 publications

References 2 publications

Long‐term kidney transplant survival in patients with continent urinary diversion

Long‐term kidney transplant survival in patients with continent urinary diversion

RETRACTED ARTICLE: Long-term results of standard procedures in urology: the ileal neobladder

Long-term results of standard procedures in urology: the ileal neobladder

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