OS096. Characteristics of hypertensive disorders in twin versus singleton pregnancies

Foo, J.Y.; Mangos, George; Brown, Mark

doi:10.1016/j.preghy.2012.04.097

Cited by 6 publications

(1 citation statement)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…67 In terms of perinatal mortality, there was no difference. 68 The risk of PE was higher in twin pregnancies with chronic hypertension than in singleton pregnancies (P < 0.01). The risk of PE was higher in twin pregnancies with chronic hypertension than in singleton pregnancies (P < 0.01).…”

Section: Influence Of Preeclampsia On Perinatal Outcome Of Twins Pregnant Womenmentioning

confidence: 95%

A Review of Research Progress of Pregnancy with Twins with Preeclampsia

Wang

Shen

2021

RMHP

View full text Add to dashboard Cite

Preeclampsia has a significant long-term effect on the health of both mothers and babies. Preeclampsia-related pregnancy complications increase the morbidity and mortality of pregnant women and their fetuses by 5-8%. The recent advancement of assisted reproductive technology, combined with a rise in the number of elderly pregnant women, has resulted in pregnancy incidence with twins. Twins pregnant women have a 2-3 times greater risk of developing preeclampsia than singleton pregnant women, and it happens sooner and progresses faster. It is more severe and may appear in an atypical way. End-organ damage, such as renal failure, stroke, cardiac arrest, pulmonary edema, placental abruption, and cesarean section, are related maternal complications. Fetal growth retardation, stillbirth, and premature delivery with obstetric signs are all fetal complications. According to studies, all multiple pregnancies can take low-dose aspirin (60-150 mg) to minimize the risk of preeclampsia. To improve pregnancy outcomes and reduce the inherent risk of pregnancy with twins, twins should be handled as a high-risk pregnancy and treated differently than singletons. The literature on twin pregnancy with preeclampsia is the subject of this review. It will examine the current state of research on preeclampsia in pregnancy with twins, including the occurrence, diagnosis, and pathophysiological process. Moreover, the effect of pregnancy with twins on the perinatal outcome and pregnancy management of pregnancy with twins, including blood pressure management and preeclampsia prevention and treatment, is examined in this literature review. The goal is to figure out what kind of diagnosis and care you may need.

show abstract

Section: Influence Of Preeclampsia On Perinatal Outcome Of Twins Pregnant Womenmentioning

confidence: 95%

A Review of Research Progress of Pregnancy with Twins with Preeclampsia

Wang

Shen

2021

RMHP

View full text Add to dashboard Cite

show abstract

Maternal outcome in multiple versus singleton pregnancies in Northern Tanzania: A registry-based case control study

Chiwanga

Massenga

Mlay

et al. 2014

Asian Pacific Journal of Reproduction

View full text Add to dashboard Cite

Placental Component and Pregnancy Outcome in Singleton versus Twin Pregnancies Complicated by Preeclampsia

Weiner¹,

Feldstein²,

Schreiber

et al. 2017

Fetal Diagn Ther

View full text Add to dashboard Cite

Objective: To compare placental histopathological lesions and pregnancy outcomes in singleton and twin pregnancies complicated by preeclampsia (PE). Methods: Maternal characteristics, neonatal outcomes, and placental histopathology reports of pregnancies complicated by PE between January 2008 and October 2016 were reviewed. Results were compared between singletons (singleton group) and dichorionic-diamniotic twins (twin group). Placental lesions were classified into maternal and fetal vascular supply lesions. Small for gestational age (SGA) was defined as birth weight ≤10th percentile. Composite adverse neonatal outcome was defined as one or more early neonatal complications. Results: Compared to the twin group (n = 67), the singleton group (n = 275) was characterized by lower maternal age (p = 0.003), higher gestational age (p < 0.001), higher rates of previous PE (p = 0.017), chronic hypertension (p = 0.036), and severe features (p < 0.001). Placentas from the singleton group were characterized by higher rates of maternal vascular malperfusion lesions (p < 0.001) and fetal vascular supply lesions (p = 0.002). Using multivariable regression analysis, composite maternal and fetal vascular malperfusion lesions were independently associated with singletons (aOR = 2.7, 95% CI = 1.2-7.8, p < 0.001, and aOR = 1.2, 95% CI = 1.2-5.6, p = 0.025, respectively). SGA was more common in the singleton group (p = 0.002). Neonatal outcome did not differ between the groups. Conclusion: Placentas from singleton pregnancies complicated by PE were characterized by higher rates of maternal and fetal vascular lesions compared to those from twin pregnancies, suggesting that different mechanisms participate in the development of PE in these two groups.

show abstract

OS096. Characteristics of hypertensive disorders in twin versus singleton pregnancies

Cited by 6 publications

References 19 publications

A Review of Research Progress of Pregnancy with Twins with Preeclampsia

A Review of Research Progress of Pregnancy with Twins with Preeclampsia

Maternal outcome in multiple versus singleton pregnancies in Northern Tanzania: A registry-based case control study

Placental Component and Pregnancy Outcome in Singleton versus Twin Pregnancies Complicated by Preeclampsia

Contact Info

Product

Resources

About