Oscillation of solutions of the second-order linear functional-difference equations

Synthesis and Anticancer Activity of Isatin, Oxadiazole and 4-Thiazolidinone Based Conjugates

“…Thus, the synthesis of new non-condensed systems with 4-thiazolidinone, 1,3,4-oxadiazole, and indoline moieties 3a-g were performed, using standard Knoevenagel reaction procedure (medium -acetic acid, catalyst -fused sodium acetate). 2-Chloro-N-(5-aryl-1,3,4-oxadiazol-2-yl)-acetamides 1a-d were tested as alkylating agents in the reaction with isatin, 5-chloroisatin and 5-bromoisatin in DMF medium at room temperature [28]. The corresponding 1-[2-(5-aryl-1,3,4-oxadiazol-2-yl)-2-oxoethyl]-1H-indole-2,3-diones 4a-h have been obtained according to Scheme 1.…”