Osseous manifestations of sarcoidosis

Radkowski, Marcin; Slawinski, Piotr R.; Targowski, Tomasz

doi:10.5114/reum.2020.95363

Cited by 22 publications

(38 citation statements)

References 76 publications

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“…2 However, in some studies, it may affect axial skeleton, skull, long bones, and ribs. 3 The pelvic form as in our case is not classical and tends to be similar to inflammatory sacroiliitis secondary to spondyloarthropathy or infectious sacroiliitis (favored by long-term corticosteroid therapy). In the literature, bone sarcoidosis and inflammatory sacroiliitis might be associated in young patients.…”

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confidence: 60%

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Pelvic and Lumbar Pain Revealing Bone Sarcoidosis: A Case Report

Charifi

Dkhissi

Haloua

et al. 2021

Clin Med Insights Case Rep

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A 54-years-old woman suffered from a bilateral pelvic and lumbar pain. She had a systemic investigation shows a diffuse bone lesions. A biopsy of iliac bone was done and revealed sarcoidosis. Bony manifestations of sarcoidosis are rare and challenging to diagnose. Our report shows that MRI with diffusion weighted sequences is a simple and non invasive technique to evaluate bone infiltration. It helps to distinguish inflammatory disease from metastatic lesions and to guide the osseous biopsy. Moreover, fluorodeoxyglucose PET scan, are useful in establishing the extent of damage and measuring disease activity.

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mentioning

confidence: 60%

“… 2 However, in some studies, it may affect axial skeleton, skull, long bones, and ribs. 3 …”

Section: Discussionmentioning

confidence: 99%

Pelvic and Lumbar Pain Revealing Bone Sarcoidosis: A Case Report

Charifi

Dkhissi

Haloua

et al. 2021

Clin Med Insights Case Rep

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“…Decreased muscle mass may appear together with decreased bone mass, in what has been named osteosarcopenia [40,41], but the relationship of sarcopenia, low BMD, and osteoporosis in RA patients is not fully established understood [42].…”

Section: Bone Mineral Densitymentioning

confidence: 99%

Sarcopenia, immune-mediated rheumatic diseases, and nutritional interventions

et al. 2021

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Introduction Sarcopenia is defined by a loss of muscle mass and function associated with mortality, decreased physical performance, falls, and disability. Since chronic inflammation and decreased physical activity are risk factors for developing sarcopenia, it is critical to assess the role of sarcopenia in immune-mediated rheumatic diseases (IMRDs). Moreover, nutritional interventions are emerging as key modifiable and affordable options to improve physical performance in sarcopenia. Objective The aim of this review is to critically summarize current information on the evidence linking nutritional interventions and sarcopenia in IMRDs. Methods The search and selection of articles was performed in Medline, Dimensions.ai, Google Scholar, Cochrane Library, Epistemonikos, and Trip Database. The results were clustered into three areas: sarcopenia and IMRDs, sarcopenia and biological disease-modifying antirheumatic drugs (bDMARDs), and nutritional interventions for sarcopenia. Findings Several cross-sectional studies have shown a higher prevalence of sarcopenia in IMRDs, such as rheumatoid arthritis. Although not fully established, evidence linking sarcopenia and other IMRDs (ankylosing spondylitis and systemic sclerosis) has been also described. For secondary sarcopenia prevention and treatment, bDMARDs’ administration proved efficacy in patients with rheumatoid arthritis. Furthermore, there is growing evidence linking nutrition to the prevention and treatment of sarcopenia. Evidence linking unfavourable results in nutritional risk assessment, insufficient intake of protein, vitamin D, antioxidant nutrients, and long-chain polyunsaturated fatty acids and sarcopenia have been reported. Conclusion Given that sarcopenia and IMRDs have strong links, further research is needed to improve patient care.

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“…However, occult sarcoidosis involvement revealed in patients investigated by 18F FDG-PET is more common. Overt osseous sarcoidosis is most often expressed at the clinical level by pain and deformed fingers, and on radiography by typical cystic lesions or moth-eaten patterns in the phalange heads of hands and toes, sometimes with surrounding soft tissue swelling [ 64 ]. These manifestations occur after several years of evolution in sarcoidosis, particularly in association with lupus pernio or sinonasal sarcoidosis.…”

Section: Diagnosis Of Extrapulmonary Organ Sarcoidosismentioning

confidence: 99%

How to Tackle the Diagnosis and Treatment in the Diverse Scenarios of Extrapulmonary Sarcoidosis

et al. 2021

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Extrapulmonary sarcoidosis occurs in 30-50% of cases of sarcoidosis, most often in association with pulmonary involvement, and virtually any organ can be involved. Its incidence depends according to the organs considered, clinical phenotype, and history of sarcoidosis, but also on epidemiological factors like age, sex, geographic ancestry, and socio-professional factors. The presentation, symptomatology, organ dysfunction, severity, and lethal risk vary from and to patient even at the level of the same organ. The presentation may be specific or not, and its occurrence is at variable times in the history of sarcoidosis from initial to delayed. There are

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Osseous manifestations of sarcoidosis

Cited by 22 publications

References 76 publications

Pelvic and Lumbar Pain Revealing Bone Sarcoidosis: A Case Report

Pelvic and Lumbar Pain Revealing Bone Sarcoidosis: A Case Report

Sarcopenia, immune-mediated rheumatic diseases, and nutritional interventions

How to Tackle the Diagnosis and Treatment in the Diverse Scenarios of Extrapulmonary Sarcoidosis

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