Osseous sarcoidosis of the foot: detection by MR imaging.

Blacksin, Marcia F.; Acello, A N; Kowalec, J; Lyons, Michael M.

doi:10.2214/ajr.163.6.7992744

Cited by 6 publications

(6 citation statements)

References 2 publications

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“…Descriptions of MRI findings of largebone sarcoidosis are primarily in case reports, more often of the spine [1][2][3][4][5][6][7] than the appendicular skeleton [8][9][10][11][12][13]. Musculoskeletal involvement can be symptomatic or asymptomatic.…”

Section: Objectivementioning

confidence: 99%

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MRI of Sarcoidosis Patients with Musculoskeletal Symptoms

Moore

Teirstein

Golimbu

2005

American Journal of Roentgenology

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In sarcoidosis patients with musculoskeletal complaints, MRI reveals marrow and soft-tissue lesions that are occult or underestimated on radiographs. Axial and large-bone lesions may resemble osseous metastases on MRI. Most lesions detected are nonspecific in appearance, except nodular muscle lesions. MRI reveals features suggesting the diagnosis, but with standard protocols, no pathognomonic MRI features were determined.

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Section: Objectivementioning

confidence: 99%

“…Descriptions of MRI findings of largebone sarcoidosis are primarily in case reports, more often of the spine [1-7] than the appendicular skeleton [8][9][10][11][12][13]. In sarcoidosis patients with musculoskeletal complaints, MRI reveals marrow and soft-tissue lesions that are occult or underestimated on radiographs.…”

mentioning

confidence: 99%

MRI of Sarcoidosis Patients with Musculoskeletal Symptoms

Moore

Teirstein

Golimbu

2005

American Journal of Roentgenology

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“…Sarcoidosis in the bone appears hypointense on T1-weighted images and hyperintense on T2-weighted images. 112,123,134 In a retrospective analysis of 52 patients with sarcoidosis who underwent MRI of the spine, abnormal bone marrow intensity was found in 7 (14%). 135 In a prospective study, 24 patients with sarcoidosis and musculoskeletal complaints had MRI scans and plain radiographs; plain radiographs missed lesions in approximately 60% of the subjects.…”

Section: Other Imaging Proceduresmentioning

confidence: 99%

“…One advantage of MRI over scintigraphy is the ability of MRI to differentiate articular, synovial, and other etiologies from direct bone involvement. 112,134 MRI also identifies potential target areas for biopsy and allows one to distinguish if the area of concern contains a focal mass or tumor. In an earlier review of osseous sarcoidosis, Barnard and Newman concluded that scintigraphy "may be superior in detecting multiple sites of bone involvement, where as MRI offers greater precision if biopsies are to be performed."…”

Section: Other Imaging Proceduresmentioning

confidence: 99%

Sarcoidosis Involving the Musculoskeletal System

Zisman¹,

Shorr²,

Lynch³

2002

Seminars in Respiratory and Critical Care Medicine

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Although sarcoidosis can affect virtually any organ, musculoskeletal involvement is infrequent. Early in the course of the disease, acute polyarthritis may be observed in up to 40% of patients, but this is often self-limited. Chronic or recurrent sarcoid arthritis is rare, affecting only 1 to 4% of patients. Asymptomatic involvement of muscles has been reported in 25 to 75% of patients in small series, but symptomatic involvement of muscles is rare. Although prospective studies assessing the prevalence of muscle involvement in sarcoidosis have not been done, several large retrospective studies suggest that symptomatic muscle involvement occurs in < 0.5% of patients with sarcoidosis. Patterns of sarcoid muscle involvement include chronic, progressive myopathy; nodular or tumorous sarcoidosis affecting muscles; and an acute polymyositis-like syndrome. Corticosteroid therapy is usually efficacious for the acute myositis variant but is less consistently helpful in the other forms (e.g., chronic myopathy or nodules). Similarly, clinically significant involvement of bone is rare (< 2-5%), and is often associated with chronic multisystemic disease, lupus pernio, and chronic uveitis. Unfortunately, osseous sarcoidosis is often unresponsive to therapy. In this review, we discuss the prevalence, clinical features, and management of sarcoidosis involving muscle, joints, and bones.

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“…141 MRI scans are very sensitive to detect osseous sarcoidosis, with enhanced activity following gadolinium. 1,143 (►Figs. 54 and 55).…”

Section: Bonementioning

confidence: 99%

Radiographic and Histopathologic Features in Sarcoidosis: A Pictorial Display

Shaikh

Abtin

Saggar

et al. 2020

Semin Respir Crit Care Med

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Sarcoidosis is a multisystemic granulomatous disorder that can affect virtually any organ. However, pulmonary and thoracic lymph node involvement predominates; abnormalities on chest radiographs are present in 80 to 90% of patients with sarcoidosis. High-resolution computed tomographic (HRCT) scans are superior to chest X-rays in assessing extent of disease, and some CT features may discriminate an active inflammatory component (which may be amenable to therapy) from fibrosis (for which therapy is not indicated). Typical findings on HRCT include micronodules, perilymphatic and bronchocentric distribution, perihilar opacities, and varying degrees of fibrosis. Less common findings on CT include mass-like or alveolar opacities, miliary opacities, mosaic attenuation, honeycomb cysts, and cavitation. With progressive disease, fibrosis, architectural distortion, upper lobe volume loss with hilar retraction, coarse linear bands, cysts, and bullae may be observed. We discuss the salient CT findings in patients with sarcoidosis (with a major focus on pulmonary features) and present classical radiographic and histopathological images of a few extrapulmonary sites.

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Osseous sarcoidosis of the foot: detection by MR imaging.

Cited by 6 publications

References 2 publications

MRI of Sarcoidosis Patients with Musculoskeletal Symptoms

MRI of Sarcoidosis Patients with Musculoskeletal Symptoms

Sarcoidosis Involving the Musculoskeletal System

Radiographic and Histopathologic Features in Sarcoidosis: A Pictorial Display

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