Ossified Mucin-secreting Choroid Plexus Adenoma: Case Report

Abstract

This is the first report of a fully documented case of an ossified mucin-producing benign choroid plexus tumor. This was a chance finding in a man who complained only of posttraumatic low back discomfort. The ossification of the tumor appears to have been therapeutic. Mucin production may be a defense mechanism. (Neurosurgery 29:130-132. 1991)

Cytokeratin 7 and 20 Expression in Choroid Plexus Tumors: Utility in Differentiating These Neoplasms from Metastatic Carcinomas

“…They may exhibit a wide spectrum of histologic patterns, including acinar (3,4), mucussecreting (5,6), oncocytic (7,8), pigmented (9,10), tubular (11), and metaplastic (5,12,13) variants. Distinguishing these tumors from metastatic carcinomas, a matter of considerable therapeutic and prognostic significance, therefore can be problematic.…”

Choroid Plexus Adenoma of the Fourth Ventricle

“…Choroid plexus adenoma is a rare, usually avascular neoplasm typically arising from the 4th ventricle or the body of the lateral ventricle [1][2][3][4][5][6][7][8][9][10][11]. A tumor arising in the 3rd ventricle has been described [10].…”

“…Gender, age (years) Location Imaging modality and findings Hoenig et al, 1967 [1] M, 68 4th ventricle Pneumoencephalography: "absence of ventricular filling" Davis & Fox, 1970 [2] M, 22 Lateral ventricle Ventriculography: "filling defect" Ajir et al, 1982 [3] M, 72 4th ventricle CT: "cystic lesion with ring-like enhancement" Eljamel & Jeffreys, 1990 [4] F, 3 Lateral ventricle CT: "cyst with enhancing thin capsule" Andreini et al, 1991 [5] M, 26 4th ventricle CT: "round lesion filling the 4th ventricle" Duckett et al, 1991 [6] M, 42 4th ventricle MRI: "ossified lesion" Varga et al, 1996 [7] M, 0.33 Lateral ventricle MrI: "partly cystic, enhancing mass" Sutton et al, 1998 [8] M, 12 Lateral ventricle MrI: "extremely vascular lesion" Varga & Vajtai, 1999 [9] N, 0.25 Lateral ventricle no data given Aquilina et al, 2005 [10] M, 0.66 3rd ventricle MrI: "partly cystic, partly enhancing tumor" rembao-Bojórquez et al, 2007 [11] M, 79 4th ventricle MrI: "cyst with enhancing nodule" CT computed tomography, F female, M male, MRI magnetic resonance imaging…”

Ossified choroid plexus papilloma of the fourth ventricle: elucidation of the mechanism of osteogenesis in benign brain tumors

“…1,22 Previously, osteogenesis in CPPs has been suggested as an autotherapeutic mechanism in reaction to the tumor cells. 6 This theory that osseous metaplasia is a result of abnormal process or injury could explain the similar features seen in both lesions.…”

“…6 Also of note, papillomas have rarely been described to have chondrometaplasia and adipose metaplasia. Cartilaginous metaplasia has been found in 2 previous cases.…”