Osteo-odonto-keratoprosthesis surgery: a combined ocular–oral procedure for ocular blindness

Osteo-odonto-keratoprosthesis – A maxillofacial perspective

“…This too confers stability to the osteodental alveolar bone lamina and prevents formation of retroprosthetic membranes (Falcinelli et al, 2005). Epithelial down-growth between the mucosal surface and the edge of the device is prevented by the presence of the intact periodontal ligament (Tay et al, 2007). The buccal mucosal graft is more physiological than other coverings, i.e., fascia lata, donor sclera, etc.…”

Osteo-odonto-keratoplasty: A Review

“…The oral assessment must take into account both the buccal mucosal graft donor site and a selection of an appropriate tooth to form a dentine/bone lamina. Buccal mucous membrane can be classified as being normal, scarred or diseased [9]. Some diseases affecting buccal mucous membrane are recurrent aphthous ulceration, leukoplakia, lichen planus and oral submucous fibrosis.…”

“…The original OOKP technique was pioneered by the late Italian surgeon Benedetto Strampelli MD in 1963 [5,9]. OOKP is an eterotopic autograft and the term stands for osteo (bone)-odonto (tooth)-kerato (cornea) prosthesis (artificial device) [10] and thus the technique is also known as "a tooth for an eye" technique [11,12].…”

“…OOKP surgery is usually the last resort for severe, end-stage corneal blindness, where other treatments such as corneal grafts [14], stem cell and amniotic membrane transplantations [15,16] and other forms of ocular surface reconstruction surgery have failed, or will not be successful [9].…”

In vivo evaluation of titanium oxide and hydroxyapatite as an artificial cornea skirt

“…Patients with these conditions do not benefit from conventional corneal transplantation with or without epithelial stem cell reconstruction, due to the severe dry eye environment, eyelid abnormalities, vascularized and inflamed corneas in these conditions [1][2][3][4]. OOKP surgery involves harvesting an autologous canine tooth with attached maxillary bone, and using this as a peripheral skirt to secure a polymethylmethacrylate (PMMA) optical cylinder.…”