Osteochondral Allografts With an Intramedullary Muscle Flap in Rabbits

Dm, Brown; Sh, Chung; La, Lantieri; Tk, Sampath; Hodge, Jacqueline C.; Nm, Kania; Mw, Vannier; Rk, Khouri

doi:10.1097/00003086-199701000-00037

Cited by 4 publications

(1 citation statement)

References 26 publications

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“…Nesse aspecto, a musculatura apresenta capacidade de fornecer células tronco mesenquimais, que permitem o início da formação óssea em resposta aos fatores osteogênicos existentes no enxerto homólogo transplantado (BROWN et al, 1997).…”

Section: Introductionunclassified

Matriz óssea homóloga desmineralizada na preparação de falhas ósseas segmentares produzidas no rádio de coelhos

et al. 2003

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RESUMONo presente trabalho, foram avaliados os potenciais osteoindutor e osteocondutor da matriz óssea homóloga desmineralizada (MOD) em ácido clorídrico 0,6 N e conservada em etanol 70% e sua utilização no preenchimento de falhas osteoperiosteais induzidas em rádio de coelhos. O rádio operado de todos os animais foi radiografado imediatamente após a cirurgia e na 3ª,6ª, 9ª e 12ª semanas após. No grupo tratado, sete animais foram sacrificados a cada três semanas, sendo realizadas tomografia computadorizada e avaliações macro e microscópica e da fluorescência óssea à tetraciclina. Os animais do grupo controle foram sacrificados na 12ª semana de pós-operatório. Foi constatado que a matriz acelerou o processo de formação óssea, devido a fatores indutores inerentes que atuaram sobre as células dos tecidos adjacentes e que os canais vasculares, as lacunas e o canal medular vazios da MOD, serviram de arcabouço para a penetração celular, determinando osteocondução.Palavras-chave: falhas ósseas, enxerto ósseo, reparação óssea. ABSTRACTIn order to evaluate osteoinduction and osteoconduction of the homologous demineralized bone matrix (DBM), processed in HCl 0.6 N solution for 24 hours and preserved in 70% ethanol solution, radial fragments were implanted in radius of adults rabbits. The animals were sacrificed at 3, 6, 9 and 12 post-operative weeks and the control group was sacrificed in 12 post-operative weeks. Radiographic exams of the operated radii were performed immediately after surgery and 3, 6, 9 and 12 post-operative weeks. After euthanasia, computed tomography, macroscopic, microscopic and tetracycline fluorescence exams were performed. DBM preserved its osteoinductive property and remains sterile. The empty spaces are favorable to osteoconduction and its growth factors induce osseous formation.

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Section: Introductionunclassified

Matriz óssea homóloga desmineralizada na preparação de falhas ósseas segmentares produzidas no rádio de coelhos

et al. 2003

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Norian Craniofacial Repair System: Compatibility with Resorbable and Nonresorbable Plating Materials

Genecov

Kremer

Agarwal

et al. 2007

Plastic and Reconstructive Surgery

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Microvascular Free Tissue Transfer: Results in 57 Consecutive Cases

Walshaw

et al. 1998

Veterinary Surgery

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The success of microvascular tissue transfer in this case series compares favorably with those reported in human reconstructive microsurgery. Both the primary and assistant surgeon should be practiced in microsurgical technique. Failure of latissimus dorsi flaps was not likely caused by an inherently deficient flap design, but was more likely attributed to the location and severity of trauma at the recipient site, the difficulty in isolating suitable recipient vessels for anastomosis or the absence of a trained assistant surgeon during these procedures. Clinical Relevance-This retrospective study documents the successful application of microvascular technique in a series of clinical cases requiring tissue reconstruction.

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Osteochondral Allografts With an Intramedullary Muscle Flap in Rabbits

Cited by 4 publications

References 26 publications

Matriz óssea homóloga desmineralizada na preparação de falhas ósseas segmentares produzidas no rádio de coelhos

Matriz óssea homóloga desmineralizada na preparação de falhas ósseas segmentares produzidas no rádio de coelhos

Norian Craniofacial Repair System: Compatibility with Resorbable and Nonresorbable Plating Materials

Microvascular Free Tissue Transfer: Results in 57 Consecutive Cases

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