“…It sometimes dcvclops during advanced pulmonary disease, particularly malignant pulmonary tumors. Altogcthcr about a hundred cases of pachydermoperiostosis have been described; exhaustive surveys of the disease have been given by several authors, including Schilling et al (91), l'ornblom et al (103) and Vogl and Goldfischer (1 11). It was first reported in the mid-nineteenth century, and there was much dispute about its origin among the famous clinicians of the time, including Friedreich, Erb, Virchow, Sternberg, and Marie.…”