Osteogenesis Imperfecta and Pregnancy: Problems Evolving by the Time of Delivery

Мравян, С. Р.; Шугинин, И. О.; Новикова, С. В.; Упрямова, Е. Ю.; Будыкина, Т. С.; Жученко, Л. А.

doi:10.18786/2072-0505-2015-37-47-51

Cited by 1 publication

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“…The first type of OI is the lightest and most common form of the disease, after which by severity of complications follow 2-, 3-and 4-th types. Recently, types 5, 6, 7 and 8 have been classified, which have the same clinical features as the 4th, but each has unique histological and genetic data [3,4,5].…”

Section: Discussionmentioning

confidence: 99%

“…Cases of uterine ruptures in patients with the 1 st type of OI are described [4,5], which may be due to the decreased collagen content in uterine myometrium in comparison with the healthy pregnant women [6]. Complications that develop during gestation include bleeding, bone fractures, uterine ruptures, uterine atony, uterine bleeding, hypothyroidism, aortic aneurysm ruptures.…”

Section: Discussionmentioning

confidence: 99%

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Peripartum Anesthetic Management of Patient with Osteogenesis Imperfecta: Case Report and Literature Review

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AV²,

KA³

2022

austiniobstetgynecol

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Osteogenesis Imperfect (OI) (Brittle Bones Disease) is the most common hereditary connective tissue disease. The main clinical forms of OI are quantitative and qualitative anomalies of type I collagen, the most common protein in bones [8]. In modern literature, cases of successful delivery of patients with imperfect osteogenesis are described, however this disease is considered a contraindication to pregnancy, and when it is advised, an artificial interruption is recommended. Such tactic is associated with the occurrence of a significant number of complications, during pregnancy and delivery, sometimes fatal for both the mother and the fetus [8]. Caesarean section is conducted more often in such patients due to maternal pelvic deformity, cephalopelvic disproportion, abnormal fetal position variants [1,8]. In literature, there are few cases of an anesthetic aid for Cesarean Section (CS) in patients with OI (types 3-4). The clinical observation that is presented, describes features of labor management of a patient with OI type IV.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%