Osteogenic Sarcoma in a Patient Injected with Thorotrast

Altner, Peter C.; Simmons, David J.; Lucas, H.F.; Cummins, H.T.

doi:10.2106/00004623-197254030-00025

Cited by 10 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It was fibrosarcoma of the ninth dorsal vertebrae in a patient who also had a hepatocholangioma. The third one was an osteoblastic sarcoma of the right tibia (Altner et al 1972). The third one was an osteoblastic sarcoma of the right tibia (Altner et al 1972).…”

Section: Bone Sarcomasmentioning

confidence: 97%

Malignancies in Portuguese Thorotrast Patients

Horta¹,

Horta²,

Motta³

et al. 1978

Health Physics

View full text Add to dashboard Cite

Of 2434 individuals who received Thorotrast in Portugal, mostly from 1930 to 1950, 1237 (or 51%) have been traced and followed up. As of 31 March 1974,931 of these had died: 16 from local Thorotrast granulomas, 25 from liver cirrhosis or fibrosis. 121 from malignant solid tumors (including 6 on the edge of large Thorotrast deposits, 75 tumours of the liver and other reticuloendothelial tissues, 5 bronchial carcinomas, 4 bone turnours, and 31 other solid tumours), 23 from fatal blood dyscrasias (including 12 leukemias, 8 aplastic anemias, and 3 other fatal blood diseases). These causes of death are significantly above the corresponding expected number in the general Portuguese population, and in a control group of 829 traced individuals injected with a non-radioactive contrast drug and followed up concomitantly.

show abstract

Section: Bone Sarcomasmentioning

confidence: 97%

Malignancies in Portuguese Thorotrast Patients

Horta¹,

Horta²,

Motta³

et al. 1978

Health Physics

View full text Add to dashboard Cite

show abstract

“…(2) In consideration of the familial sarcoma-carcinoma syn¬ drome, the child's mother and pater¬ nal aunt should have breast examina¬ tions, and records of the young cousin who died, of an unspecified malignant neoplasm should be reviewed. (3) Fibroblasts from father, daughter, and first-degree relatives should be obtained so that cell cultures can be evaluated for abnormalities indicative of increased cancer risk (for example, defects in the repair of radiationinduced DNA damage) and so that they can then be stored for appro¬ priate tests in the future. (4) Sera should be saved for special assays for NF as they are developed or improved (eg, nerve growth factor).…”

Section: Recommendationsmentioning

confidence: 99%

Sarcomas in a Child and Her Father

Parry¹

1979

Am J Dis Child

View full text Add to dashboard Cite

We are pleased to present this unusual article by an author who is a leader in the field of childhood cancer, particularly those aspects having to do with epidemiology and associated malformation. This "etiologic consultation" by Robert W. Miller, MD, and his associates will whet your intellectual appetite, and thus possibly generate ideas forfuture "consultations" in this and other areas of pediatrics.\p=m-\Ed.

show abstract

Thorotrast-induced extraskeletal osteosarcoma of the cervical region.Report of a case

Hasson

Milikow

et al. 1975

Cancer

View full text Add to dashboard Cite

This is the seventh reported case of soft tissue sarcoma attributed to thorotrast extravasated during the course of an injection for arteriography. An extraskeletal osteosarcoma occurring the cervical region of a 51-year-old man 30 years after a cerebral arteriogram is presented. The other reported cases include a fibrosarcoma, two neurofibrosarcomas, two spindle cell sarcomas, and an extraskeletal chondrosarcoma. The latency period has varied from 5 to 30 years. The thorotrast granules are readily identified in macrophages near or adjacent to the tumor, and the demonstration of alpha tracks on autoradiographs is diagnostic.

show abstract

Osteogenic Sarcoma in a Patient Injected with Thorotrast

Cited by 10 publications

References 0 publications

Malignancies in Portuguese Thorotrast Patients

Malignancies in Portuguese Thorotrast Patients

Sarcomas in a Child and Her Father

Thorotrast-induced extraskeletal osteosarcoma of the cervical region.Report of a case

Contact Info

Product

Resources

About