Osteoid Osteoma: A Diagnosis for Radicular Pain of Extremities

Abstract

Osteoid osteoma is a benign tumor commonly found in young patients. The most interesting feature of the tumor is its peculiar obvious pain. The intensity of pain produced by osteoid osteoma is unproportionate to its nature and size. Much has been written about the mechanism of this symptom of the tumor and the specific characteristics of the pain that can be misleading when appearing as radicular pain especially when some subtle neurologic signs and symptoms accompany the pain. In this article, 12 patients who were referred to our clinic with radicular pain and neurological signs and symptoms months after initiation of symptoms between 2000 and 2008 are presented. Of these 12 patients, most were first thought to have root compression disease before being referred to our hospital. Precise history taking and special attention to physical examinations led to a suspicion of osteoid osteoma. Plain radiographs, computed tomography, and bone scans indicated osteoid osteoma, and excisional biopsy confirmed its diagnosis. Osteoid osteoma should always be considered in young patients with radicular pain, even with subtle neurological signs and symptoms.

Radionuclide imaging in the diagnosis of osteoid osteoma

“…However, these tumors rarely occur on the axial skeleton (8). Osteoid osteoma has unique and quite often diagnostic symptoms; the typical clinical symptom is long term pain of increasing severity (9). This pain is often referred to the nearest joint when the tumor is located in the proximity of a joint, which physicians may confuse with arthritic pain (10).…”

Preparation of Juniperus Extract and Detection of Its Antimicrobial and Antioxidant Activity

“…Erythrocytes are a main target for the free radicals due to the high membrane concentration of polyunsaturated fatty acids and the oxygen transport related with redox active hemoglobin molecules, which are strong promoters of activated oxygen species (8). The principle of this test was determined by inhibited the act of hydrogen peroxide which crosses RBC membrane and acts on intracellular moiety and forming ferryl radical or hydroxyl radical through interacting with hemoglobin and initiates a series of reactions resulted in RBC lysis (haemolysis) and discharge hemoglobin in to the supernatant ( 30).…”

Comparison of Noninvasive High-Intensity Focused Ultrasound with Radiofrequency Ablation of Osteoid Osteoma

“…Distribution of lesion locations (Figure 2; available at www.jpeds.com) was consistent with that reported in the literature. 19 Patient characteristics in both groups are described in Table I. Patients in the MR-HIFU group were much older (P = .029) and heavier (P = .049) than patients in the RFA group.…”