Osteolipoma in the parapharyngeal space

Abstract

We report our experience in managing a 58-year-old Japanese woman with a rare parapharyngeal interstitial cell tumor. Her main complaint was that of a submandibular swelling, which was diagnosed as osteolipoma histologically after resection.

Osteolipoma Presenting as a Submandibular Mass: A Rare Presentation

“…Only four cases of this rare type of lipoma presented as neck masses [4,11], two of which reported in 1973 and 1998 in the submandibular area [12,13]. We are reporting the third case in this special location.…”

A huge osteolipoma involving the coronoid process: a case report

“…Under normal conditions, the existence of adipose tissue in some regions can explain the occurrence of a lipoma and subsequent osteolipoma (9). Ohno et al stated that fibrous tissue is the origin for bone changes in a lipoma (3). It is still controversial whether this disorder is a hamartoma, a neoplasm, or metaplastic.…”

“…Allen et al reported that only 6 of 635 cases with benign lipomas in their study showed ossification (2). Clinically, an osteolipoma, containing mature lamellar bones irregularly arranged in a significant fat component, is quite rare (3,4). In contrast, an ossifying lipoma usually occurs within the intrathecal bone and rarely within the cortical bone.…”

Osteochondrolipoma of the Submandibular Region: A Case Report and Review of the Literature

“…A review of the English literature found that, outside the head and neck area, lipomas with osseous differentiation have been reported in deep locations adjacent to bone tissue in the thigh [10][11][12][13], knee [14,15], sternoclavicular region [16], shoulder [17], wrist [14], hand [18], intraspinal [19] or in superficial subcutaneous tissue [20,21]. More than 60 % of the cases occur in the head and neck region, where they have been described in intraspinal [22], intracranial [23] (suprasellar/hypothalamic and interhemispheric) and extracranial-extraspinal locations [3][4][5][6][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42]. The latter are summarized in Table 1.…”

“…Admixed differentiation into a diversity of mesenchymal elements, such as fibrous tissue (fibrolipoma), blood vessels (angiolipoma) or muscle (myolipoma) is a relatively frequent event. Osseous change is extremely rare, mainly in large and long-standing lipomas [5,6]. We report our experience in managing a patient with a submandibular mass with the configuration of a lipoma and with concurrent bone and cartilaginous differentiation, consistent with an osteochondrolipoma.…”