Osteolipoma of floor of the mouth

Raghunath, Vandana; Manjunatha, Bhari Sharanesha

doi:10.1136/bcr-2015-209883

Cited by 11 publications

(7 citation statements)

References 11 publications

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“…No other markers or details on osteogenic differentiation of these cells were reported. However, there are numerous reports on lipoma tissue ossification observed in different parts of the body [8,16,18,19,60,61,62,63] and this phenomenon could be explained by the existence of stem cells in lipoma tissue that may differentiate into osteoblasts and chondrocytes.…”

Section: Discussionmentioning

confidence: 99%

Stem Cells Derived from Lipoma and Adipose Tissue—Similar Mesenchymal Phenotype but Different Differentiation Capacity Governed by Distinct Molecular Signature

Stojanović

Najman

Korać

2018

Cells

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Lipomas are benign adipose tissue tumors of unknown etiology, which can vary in size, number, body localization and cell populations within the tissue. Lipoma-derived stem cells (LDSCs) are proposed as a potential tool in regenerative medicine and tissue engineering due to their similar characteristics with adipose-derived stem cells (ADSCs) reported so far. Our study is among the first giving detailed insights into the molecular signature and differences in the differentiation capacity of LDSCs in vitro compared to ADSCs. Mesenchymal stem cell phenotype was analyzed by gene expression and flow cytometric analysis of stem cell markers. Adipogenesis and osteogenesis were analyzed by microscopic analysis, cytochemical and immunocytochemical staining, gene and protein expression analyses. We showed that both LDSCs and ADSCs were mesenchymal stem cells with similar phenotype and stemness state but different molecular basis for potential differentiation. Adipogenesis-related genes expression pattern and presence of more mature adipocytes in ADSCs than in LDSCs after 21 days of adipogenic differentiation, indicated that differentiation capacity of LDSCs was significantly lower compared to ADSCs. Analysis of osteogenesis-related markers after 16 days of osteogenic differentiation revealed that both types of cells had characteristic osteoblast-like phenotype, but were at different stages of osteogenesis. Differences observed between LDSCs and ADSCs are probably due to the distinct molecular signature and their commitment in the tissue that governs their different capacity and fate during adipogenic and osteogenic induction in vitro despite their similar mesenchymal phenotype.

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Section: Discussionmentioning

confidence: 99%

Stem Cells Derived from Lipoma and Adipose Tissue—Similar Mesenchymal Phenotype but Different Differentiation Capacity Governed by Distinct Molecular Signature

Stojanović

Najman

Korać

2018

Cells

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“…Most of the cases of osteolipoma of oral cavity presented as painless, well circumscribed, nodular masses with soft-hard in consistency ( 3 ). In our case, multiple hard nodular structures could be palpated within the soft and fluctuant lesion, which again was not reported earlier.…”

Section: Discussionmentioning

confidence: 99%

"Osteolipoma of buccal mucosa: Case report and literature review"

Raviraj¹,

Kumar-Bokkasam²,

Suresh³

et al. 2016

J Clin Exp Dent

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Osteolipoma affecting oral cavity is indeed rare. We hereby report a case of osteolipoma affecting buccal mucosa. A review of literature of osteolipoma of oral cavity, particularly on radiographic/imaging findings was done. Only 16 cases of Osteolipoma of oral cavity are reported in the literature. The radiographic findings of our case, i.e. multiple dense homogenous radio-opaque structures was reported earlier only in one case [out of 16] of osteolipoma of oral cavity. Key words:Lipoma, osteolipoma, panoramic radiography, radio-opaque, radiography.

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“…To the best of our knowledge, only 7 cases of OL of the major salivary gland regions have been reported in the actual literature. 6,[10][11][12][13][14][15] We report in Supplementary Digital Content Table 1, http:// links.lww.com/SCS/C441 the actual literature about OL in major salivary glands.…”

Section: Discussionmentioning

confidence: 99%

“…The OL has been widely described in various anatomical district sites of the body, such as the upper and lower extremities, spine, subcutaneous soft tissue and, very rarely, in head and neck region 2–5 . In particular, in the head and neck district, OL has been reported as a lesion located in the parapharyngeal space, nasopharinx, submandibular gland, eyelid, floor of the mouth, and skull base 6–10 …”

mentioning

confidence: 99%

Intraparotid Osteolipoma: Treatment Option and Surgical View

Battaglia

Crimi

Nocini

et al. 2021

Journal of Craniofacial Surgery

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Osteolipoma is a benign neoplasm originating from the mesenchymal fat tissue cells and characterized by the presence of bone formation. In the head and neck district osteolipoma has been described as parapharyngeal, nasopharinx, submandibular gland, eyelid, floor of the mouth, and skull base lesion. Only 1 case of osteolipoma was reported as a neoplasm of the parotid region. Considering the rarity of the osteolipoma, our purpose was to describe the first case of totally intraparotid gland localization of osteolipoma and summarize and review the actual literature concerning the presence of this tumor in the region of major salivary glands. A 56-years-old male patient was treated for intraparotid osteolipoma. Surgical removal of tumor was done with a standard preauricular/cervical incision and blunt dissection. The facial nerve was identified and preserved completely. In the reviewed series, all cases were reported in adult patients with a relative long history of slow progression. According to our paper and the review of the literature, we can assess that Osteolipoma is an extremely rare lesion affecting the major salivary glands, which should be considered along with common salivary gland tumors in the differential diagnosis.

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Osteolipoma of floor of the mouth

Cited by 11 publications

References 11 publications

Stem Cells Derived from Lipoma and Adipose Tissue—Similar Mesenchymal Phenotype but Different Differentiation Capacity Governed by Distinct Molecular Signature

Stem Cells Derived from Lipoma and Adipose Tissue—Similar Mesenchymal Phenotype but Different Differentiation Capacity Governed by Distinct Molecular Signature

"Osteolipoma of buccal mucosa: Case report and literature review"

Intraparotid Osteolipoma: Treatment Option and Surgical View

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