1971
DOI: 10.7326/0003-4819-75-5-693
|View full text |Cite
|
Sign up to set email alerts
|

Osteomyelitis in Heroin Addicts

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

1
15
0
1

Year Published

1973
1973
2010
2010

Publication Types

Select...
10

Relationship

0
10

Authors

Journals

citations
Cited by 139 publications
(17 citation statements)
references
References 14 publications
1
15
0
1
Order By: Relevance
“…We identified similar risk factors for patients with candidal vertebral osteomyelitis: 53% of patients had central venous catheters, 50% had been treated with antibiotics, and 37% were immunosuppressed. We also identified injection drug use as a risk factor for 22% of patients, a finding consistent with previous reports that invasive candidiasis is related to parenteral drug abuse [4,7,14,24]. The remaining risk factors were a collection of clinical conditions, such as underlying malignancy, surgery, diabetes, and alcohol abuse, which theoretically predisposed the patients to develop invasive disease from normally low-virulence organisms.…”
Section: Resultssupporting
confidence: 76%
“…We identified similar risk factors for patients with candidal vertebral osteomyelitis: 53% of patients had central venous catheters, 50% had been treated with antibiotics, and 37% were immunosuppressed. We also identified injection drug use as a risk factor for 22% of patients, a finding consistent with previous reports that invasive candidiasis is related to parenteral drug abuse [4,7,14,24]. The remaining risk factors were a collection of clinical conditions, such as underlying malignancy, surgery, diabetes, and alcohol abuse, which theoretically predisposed the patients to develop invasive disease from normally low-virulence organisms.…”
Section: Resultssupporting
confidence: 76%
“…Recently, two specific infections in hemodialyzed patients, bacterial endocarditis [5] and osteomyelitis [6] have been described. Both of these infections are also common in heroin addicts and patients with chronic indwelling catheters [7][8][9]. While it is true that host defense mechanism may be altered by narcotics [10] as well as by uremic toxins [2,11], the most striking common feature of narcotic users, dialysis patients and patients with indwel ling catheters is repeated or continuous invasion of the systemic circulation.…”
Section: Discussionmentioning
confidence: 99%
“…Ambrose et al (1966) and Lewis et al (1972) successfully obtained bacterial samples by needle aspiration. Holzman & Bishko (1971) disputed the necessity of specific bacteriological diagnosis and resistance determination and thus also of early exploration. This standpoint is justified with regard to the spondylitis of addicts.…”
Section: Discussionmentioning
confidence: 99%