Ostéonécroses aseptiques, une revue générale des ostéonécroses de la hanche, et au-delà

Pijnenburg, Luc; Felten, Renaud; Javier, R.-M.

doi:10.1016/j.revmed.2019.10.332

Cited by 25 publications

(19 citation statements)

References 57 publications

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“…The condition might result from traumatic or non-traumatic factors and eventually leads to the collapse of the femoral head [ 1 , 23 , 24 ]. Furthermore, AVN of the femoral head is linked to pathological synovial reaction, hypertrophy, effusion, and an increase in intra-articular pressure [ 2 , 4 , 25 – 28 ]. To understand the correlation between intra-articular pressure of the hip joint and blood flow to the femoral head in animal models, a microsphere of radioactively-labeled red cells was used.…”

Section: Discussionmentioning

confidence: 99%

Long-term outcomes of arthroscopic synovectomy and core decompression through multiple small bone holes for early-stage avascular necrosis of the femoral head

Luo

et al. 2023

Arthroplasty

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Objective This study described a minimally invasive approach for the management of early-stage avascular necrosis of the femoral head, which integrated arthroscopic intra-articular decompression and core decompression by drilling multiple small holes. Method A total of 126 patients with 185 hip avascular necrosis were included between March 2005 and January 2008, and the hips were classified, based on the Association Research Circulation Osseous staging system, into stage I (n = 43), stage II (n = 114), and stage III (n = 28). Arthroscopic intra-articular inspection and debridement, along with drilling of multiple small holes for core decompression, were performed. The Modified Harris hip score system and radiographs were used to assess the pre- and post-surgery outcomes. Results One hundred and three patients (involving 153 hips) were followed up successfully for an average of 10.7 ± 3.4 years (range: 9–12 years). After surgery, the overall survival rate was 51.6% (79 hips), and the clinical survival rates were 79%, 72%, 52%, 32%, and 10% for patients with stage I, IIa, IIb, IIc, and III, respectively. The outcomes of patients with Association Research Circulation Osseous Stages I or IIA were better than those of other stages, while hips with a large necrotic area had poor results. This approach preserved the original biomechanical strength of the femoral head after core decompression and eliminated arthritis factors in the hip joint. Conclusion The core decompression with multiple small-size holes is an effective method for treating early-stage avascular necrosis of the femoral head, particularly in those with pathological changes in the hip joint. Level of evidence Therapeutic study, Level IV.

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Section: Discussionmentioning

confidence: 99%

Long-term outcomes of arthroscopic synovectomy and core decompression through multiple small bone holes for early-stage avascular necrosis of the femoral head

Luo

et al. 2023

Arthroplasty

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“…Delayed treatment can result in cellular apoptosis, exacerbating inflammation and predisposing to other lesions (Ref. 110 ).…”

Section: Post-traumatic Ischaemic Necrosismentioning

confidence: 99%

Trauma diagnostic-related target proteins and their detection techniques

Wei,

Ren,

Yuan

et al. 2024

Expert Rev. Mol. Med.

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Trauma is a significant health issue that not only leads to immediate death in many cases but also causes severe complications, such as sepsis, thrombosis, haemorrhage, acute respiratory distress syndrome and traumatic brain injury, among trauma patients. Target protein identification technology is a vital technique in the field of biomedical research, enabling the study of biomolecular interactions, drug discovery and disease treatment. It plays a crucial role in identifying key protein targets associated with specific diseases or biological processes, facilitating further research, drug design and the development of treatment strategies. The application of target protein technology in biomarker detection enables the timely identification of newly emerging infections and complications in trauma patients, facilitating expeditious medical interventions and leading to reduced post-trauma mortality rates and improved patient prognoses. This review provides an overview of the current applications of target protein identification technology in trauma-related complications and provides a brief overview of the current target protein identification technology, with the aim of reducing post-trauma mortality, improving diagnostic efficiency and prognostic outcomes for patients.

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“…Avascular necrosis (AVN) is a cytotoxic necrosis or ischemia of the epiphyseal bone that often affects young people, causing pain in the joints and reducing average lifetime. AVN highlights the possibility of a systemic etiology and can be either unifocal or multifocal [ 1 ]. The femoral head is affected by AVN more than 75% of the time [ 1 ].…”

Section: Introductionmentioning

confidence: 99%

“…AVN highlights the possibility of a systemic etiology and can be either unifocal or multifocal [ 1 ]. The femoral head is affected by AVN more than 75% of the time [ 1 ]. AVN of the femoral head (AVNFH) develops when the blood supply of the proximal femur is interrupted.…”

Section: Introductionmentioning

confidence: 99%

“Mulligan Bent Leg Raise” Technique in Avascular Necrosis

Karanjkar,

Dhage

2023

Cureus

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This case report examines the effectiveness of the “Mulligan bent leg raise” (MBLR) method for treating femoral head avascular necrosis (AVN). A professional physiotherapist directed a six-week rehabilitation program for a 37-year-old male patient with AVN that included this innovative physiotherapeutic method. According to radiographic results and standardized evaluations, the patient showed significant improvements in hip range of motion, functional ability, and pain levels. As a viable supplement to conventional rehabilitation techniques, the MBLR method has shown promise in improving joint function and reducing symptoms in individuals with acute compartment syndrome. The present study provides significant contributions to the discipline. It highlights the necessity for more investigation to examine the wider relevance and enduring effectiveness of this methodology in various population affected.

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Ostéonécroses aseptiques, une revue générale des ostéonécroses de la hanche, et au-delà

Cited by 25 publications

References 57 publications

Long-term outcomes of arthroscopic synovectomy and core decompression through multiple small bone holes for early-stage avascular necrosis of the femoral head

Long-term outcomes of arthroscopic synovectomy and core decompression through multiple small bone holes for early-stage avascular necrosis of the femoral head

Trauma diagnostic-related target proteins and their detection techniques

“Mulligan Bent Leg Raise” Technique in Avascular Necrosis

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