Osteoporosis in a cohort of 1062 postmenopausal women

Bouzid, Aicha; Meskine, D.

doi:10.1530/endoabs.41.ep125

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“…The phantom precision expressed as the coefficient of variation percentage was 3%. T-scores of the lumbar spine and total hip were calculated using the reference curve obtained with the French OFELY cohort [ 19 ], preferred to the US NHANES reference curve in the absence of an Algerian one, and both were previously shown to give comparable results [ 20 ]. The World Health Organization classification system was applied, defining osteoporosis as T-score ≤ −2.5 and osteopenia as T-score between −2.5 and −1 [ 21 ].…”

Section: Methodsmentioning

confidence: 99%

Hypovitaminosis D and Its Associated Factors in North Algerian Postmenopausal Women: Results of a Cross-Sectional Study

Oussedik-Lehtihet¹,

Haouichat²,

Hammoumraoui³

et al. 2017

Journal of Nutrition and Metabolism

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Purpose As the vitamin D status of Algerian postmenopausal women was poorly described, this cross-sectional study investigated the prevalence of low vitamin D status in a sample population. Secondarily, predictive factors of this hypovitaminosis D were explored. Methods All the 336 selected women ≥ 45 years from Douera were interviewed to get anthropometric and lifestyle data, reproductive and medical history, medications, and calcium/vitamin D intakes. A blood sample was collected to measure 25-hydroxyvitamin D (25(OH)D) concentrations. Results Approximately 86% of subjects had low vitamin D status (<20 ng/mL). Mean 25(OH)D level was 14.4 ± 5.3 ng/mL with a clear seasonal dynamic and a significant negative correlation with PTH levels (r = −0.15, p=0.006). A multiple regression analysis using the 25(OH)D cutoff value of 17 ng/mL instead of the generally admitted level of 20 ng/mL was performed to increase statistical power. Other seasons than summer (OR 4.159 and 95% CI 2.456–7.043), obesity (≥30 kg/m2, OR 1.826, 95% CI 1.081–3.083), and veiling (OR 3.526, 95% CI 1.090–11.400) were significantly associated with 25(OH)D concentrations <17 ng/mL. Conclusions In North Algeria, the abundant sunlight appears insufficient to fully offset hypovitaminosis D risk factors in postmenopausal women, especially obesity and veiling. It suggests the major need to increase vitamin D supplementation in this subpopulation.

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Section: Methodsmentioning

confidence: 99%