Osteoporosis, Metabolic Aberrations, and Increased Risk for Vertebral Fractures After Partial Gastrectomy

Mellström, Dan; Johansson, Christer; Johnell, Olof; Lindstedt, Göran; Lundberg, Per‐Arne; Obrant, Karl; Schöön, Ivi-Mai; Toss, Göran; Ytterberg, Bengt-Olof

doi:10.1007/bf03549778

Cited by 115 publications

(8 citation statements)

References 35 publications

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“…13 Our finding that postmenopausal smoking had more impact than premenopausal smoking is consistent with this mechanism, since the antiestrogenic effect of smoking is most prominent among postmenopausal women. 13 Smokers also may have lower levels of parathyroid hormone, 25-hydroxyvitamin D, and 1,25-dihydroxyvitamin D, [14][15][16][17] all of which could reflect increased bone resorption. Perhaps because of these hormonal characteristics, cigarette smoking (or nicotine) seems to lead to decreased calcium absorption or retention in the gut.…”

Section: Commentmentioning

confidence: 99%

Cigarette Smoking, Alcohol Consumption, and Risk of Hip Fracture in Women

Baron¹,

Farahmand²,

Weiderpass³

et al. 2001

Arch Intern Med

129

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Section: Commentmentioning

confidence: 99%

Cigarette Smoking, Alcohol Consumption, and Risk of Hip Fracture in Women

Baron¹,

Farahmand²,

Weiderpass³

et al. 2001

Arch Intern Med

129

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“…However, the mechanisms of bone disorders after gastrectomy are not fully clear, and most previous studies investigating bone disorders after gastrectomy were retrospective or cross-sectional studies without BMD data before surgery (9)(10)(11)(12)(13)(14)(15). Hence, when BMD starts to decrease and the extent of the decline remain unclear.…”

mentioning

confidence: 99%

A Gender Comparison of Bone Metabolic Changes After Gastric Cancer Surgery: A Prospective Observational Study

Atsumi

Rino

Aoyama

et al. 2021

In Vivo

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Background/Aim: This study was designed to investigate gender-related differences in changes in bone metabolism after gastric cancer surgery. Patients and Methods: We prospectively recruited 47 patients (38 males and 9 females) who had early gastric cancer. The bone mineral density (BMD), serum levels of 1,25-dihydroxy vitamin D (1,25(OH) 2 VD), 25-hydroxy vitamin D (25(OH)VD), and estradiol (E2) were measured before and after surgery. Results: BMD significantly decreased 12 months after surgery by median degrees of 3.4% and 3.9% in male and female patients, respectively (p<0.001 and p=0.023). There was no significant difference between both genders in the rate of change in BMD after surgery. The serum E2 level in male patients significantly increased by a median value of 22 pg/ml 12 months after gastrectomy (p=0.030). Both the serum 25(OH)VD and 1,25(OH) 2 VD levels remained nearly within the normal range throughout the observation period in both male and female patients. Conclusion: BMD significantly decreased within 12 months after gastrectomy in both male and female patients with gastric cancer, and there was no significant gender-related difference in the rate of change in BMD.

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“…As per our data, smokers as well as non-smokers with vitamin D de ciency were at a higher risk of developing Psoriasis. A negative effect of smoking on serum 25-hydroxy vitamin D was found in a Swedish case-control study [47]. Slightly reduced concentrations of 25-hydroxy vitamin D has been described in healthy American postmenopausal female smokers [48].…”

Section: Discussionmentioning

confidence: 99%

Vitamin D status in Psoriasis: Impact and Clinical Correlations

Bhat

Guldin

Khan

et al. 2022

Preprint

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Psoriasis is a continuing, periodic, immune‑mediated, fiery skin disease branded by hyper proliferation of epidermal keratinocytes and accompanying with inflammatory cellular infiltrate in both dermis and epidermis. Immunomodulation could be an important effect of vitamin D in Psoriasis. This case-control study was designed to measure serum 25-hydroxy vitamin D levels in patients with psoriasis and healthy controls and to find out clinical correlation, if any. Two hundred forty (n=240) subjects (120 cases and 120 controls) were taken for the study. Cases and controls were frequency matched with respect to age, gender and smoking status. Various demographic and clinical details were taken using a questionnaire. Chemiluminescence Micro Particle Immunoassay was used to estimate serum 25-hydroxy vitamin D levels. The vitamin D deficiency in psoriasis patients was 60.0% vs. 17.5% in controls (P<0.001) with mean vitamin D levels of 28.3 ± 13.9 ng/ml in psoriasis patient’s vs 37.9 ± 9.7 ng/ml in controls. Vitamin D deficiency was found to be associated with psoriasis independently of gender, age, smoking status, family history, hypertension, chronic medication, nail changes, duration of symptoms and severity of disease. Vitamin D levels were seven times lower in patients with Psoriasis as compared to controls. Reduced vitamin D levels are related to duration and clinical severity of the disease. Early detection of vitamin D deficiency and timely intervention could lead to better clinical outcome and improved quality of life in psoriasis patients.

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Osteoporosis, Metabolic Aberrations, and Increased Risk for Vertebral Fractures After Partial Gastrectomy

Cited by 115 publications

References 35 publications

Cigarette Smoking, Alcohol Consumption, and Risk of Hip Fracture in Women

Cigarette Smoking, Alcohol Consumption, and Risk of Hip Fracture in Women

A Gender Comparison of Bone Metabolic Changes After Gastric Cancer Surgery: A Prospective Observational Study

Vitamin D status in Psoriasis: Impact and Clinical Correlations

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