2020
DOI: 10.1042/bsr20202156
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Osteoprotegerin SNP associations with coronary artery disease and ischemic stroke risk: a meta-analysis

Abstract: Osteoprotegerin (OPG) is involved in the development of atherosclerosis and cardio-cerebrovascular disease. The goal of this meta-analysis was to evaluate the association of OPG single nucleotide polymorphisms (SNPs) with coronary artery disease (CAD) and ischemic stroke. A total of 15 eligible studies were extracted from electronic databases. Odds ratios (ORs) were presented, with 95% confidence intervals (CIs), to assess the associations. Meta-analysis was conducted using MetaGenyo, STATA, and Comprehensive … Show more

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Cited by 5 publications
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“…Also, serum OPG levels were significantly related to cognition [ 42 ], and the OPG SNP T245G was significantly associated with an increased risk of ischemic brain stroke [ 43 ].…”
Section: Discussionmentioning
confidence: 99%
“…Also, serum OPG levels were significantly related to cognition [ 42 ], and the OPG SNP T245G was significantly associated with an increased risk of ischemic brain stroke [ 43 ].…”
Section: Discussionmentioning
confidence: 99%