Other commonly used biomedical coatings: pyrolytic carbon coatings

Hassler, Matthew R.

doi:10.1533/9780857093677.1.75

Cited by 18 publications

(13 citation statements)

References 21 publications

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“…Numerous articles have reported satisfactory results when pyrocarbon was used for hand and wrist arthroplasty, and it has proved to be a durable material, producing little or no wear and therefore granting implant longevity 4, 10, 18. Consequently, the material properties might help prevent erosion of the glenoid surface and reduce associated pain 3, 11, 19…”

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confidence: 99%

Pyrolytic carbon humeral head in hemi-shoulder arthroplasty: preliminary results at 2-year follow-up

Garret¹,

Harly

Huec

et al. 2019

JSES Open Access

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Background In patients with osteoarthritis (OA) and an intact rotator cuff, hemi-shoulder arthroplasty (HSA) can be a viable option as it offers the advantage of keeping the native glenoid intact. However, glenoid erosion has frequently been reported. The aim of this study was to report preliminary clinical results of HSA with a new pyrolytic carbon (pyrocarbon) humeral head. Methods This prospective multicenter study included a continuous series of 65 patients who underwent pyrocarbon HSA in 5 centers. Results At the time of analysis, 1 patient was lost to follow-up, 3 patients underwent revision, and 61 patients were evaluated at a mean follow-up of 25.9 ± 3.3 months. The mean age at index surgery was 57.9 ± 13.3 years. The indications were primary glenohumeral OA in 37 patients, osteonecrosis in 11, secondary OA in 11, and rheumatoid arthritis in 2. The mean Constant score increased from 31.0 ± 15.8 points at baseline to 74.6 ± 17 points at last follow-up. Radiographic analyses showed that 86% of glenoids remained unchanged whereas 14% evolved slightly. Conclusions Pyrocarbon HSA grants improvement in pain and function in patients with primary OA or secondary OA after instability but at a lower level in patients with post-traumatic sequelae (secondary OA or osteonecrosis). These preliminary clinical and radiologic results are encouraging, although they need to be confirmed by longer-term follow-up observations.

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confidence: 99%

Pyrolytic carbon humeral head in hemi-shoulder arthroplasty: preliminary results at 2-year follow-up

Garret¹,

Harly

Huec

et al. 2019

JSES Open Access

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“…PyC deposition on various surfaces might have some limitations, because the coefficient of thermal expansion (CTE) of the coating and the substrate must be similar. Otherwise high-temperature deposition of PyC on the substrate with the too different CTE from that of PyC will lead to dimensional interferences at room temperature and stresses generation, which will compromise PyC adherence [ 35 ]. However, the deposition of PyC on bSi and SiO 2 overcomes this problem as CTE for Si, SiO 2 , and PyC is 0.54 × 10 −6 K −1 , 0.55 × 10 −6 K −1, and 0.29 × 10 −6 K −1 [ 36 ], respectively.…”

Section: Methodsmentioning

confidence: 99%

Macro-, Micro- and Nano-Roughness of Carbon-Based Interface with the Living Cells: Towards a Versatile Bio-Sensing Platform

Golubewa

Rehman

Kulahava

et al. 2020

Sensors

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Integration of living cells with nonbiological surfaces (substrates) of sensors, scaffolds, and implants implies severe restrictions on the interface quality and properties, which broadly cover all elements of the interaction between the living and artificial systems (materials, surface modifications, drug-eluting coatings, etc.). Substrate materials must support cellular viability, preserve sterility, and at the same time allow real-time analysis and control of cellular activity. We have compared new substrates based on graphene and pyrolytic carbon (PyC) for the cultivation of living cells. These are PyC films of nanometer thickness deposited on SiO2 and black silicon and graphene nanowall films composed of graphene flakes oriented perpendicular to the Si substrate. The structure, morphology, and interface properties of these substrates are analyzed in terms of their biocompatibility. The PyC demonstrates interface biocompatibility, promising for controlling cell proliferation and directional intercellular contact formation while as-grown graphene walls possess high hydrophobicity and poor biocompatibility. By performing experiments with C6 glioma cells we discovered that PyC is a cell-friendly coating that can be used without poly-l-lysine or other biopolymers for controlling cell adhesion. Thus, the opportunity to easily control the physical/chemical properties and nanotopography makes the PyC films a perfect candidate for the development of biosensors and 3D bioscaffolds.

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“…A new form of glass-like carbon (glassy carbon) has been introduced in electrochemistry for improved detection of targeted hazardous contaminants. It is an amorphous carbon allotrope produced by the controlled pyrolysis of an organic polymer, with a turbostratic structure in which poorly organised graphitic planes are arranged in ribbons as in polymers, giving rise to an isotropic material on average [ 143 , 144 , 145 ]. Krajewaska et al [ 146 ] developed an electrochemical biosensor using glassy carbon electrodes (GCE) coated with SWCNTs and haemoglobin (Hb/SWCNT/GCE) for amperometric detection of acrylamide in water solutions.…”

Section: Synthesis and Fabrication Of Npsmentioning

confidence: 99%

Gold–Carbon Nanocomposites for Environmental Contaminant Sensing

et al. 2021

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The environmental crisis, due to the rapid growth of the world population and globalisation, is a serious concern of this century. Nanoscience and nanotechnology play an important role in addressing a wide range of environmental issues with innovative and successful solutions. Identification and control of emerging chemical contaminants have received substantial interest in recent years. As a result, there is a need for reliable and rapid analytical tools capable of performing sample analysis with high sensitivity, broad selectivity, desired stability, and minimal sample handling for the detection, degradation, and removal of hazardous contaminants. In this review, various gold–carbon nanocomposites-based sensors/biosensors that have been developed thus far are explored. The electrochemical platforms, synthesis, diverse applications, and effective monitoring of environmental pollutants are investigated comparatively.

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Other commonly used biomedical coatings: pyrolytic carbon coatings

Cited by 18 publications

References 21 publications

Pyrolytic carbon humeral head in hemi-shoulder arthroplasty: preliminary results at 2-year follow-up

Pyrolytic carbon humeral head in hemi-shoulder arthroplasty: preliminary results at 2-year follow-up

Macro-, Micro- and Nano-Roughness of Carbon-Based Interface with the Living Cells: Towards a Versatile Bio-Sensing Platform

Gold–Carbon Nanocomposites for Environmental Contaminant Sensing

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