Other hyaluronic acid fillers and combination fillers

Abstract

The use of hyaluronic acid (HA) fillers has become increasingly popular in the cosmetic industry due to their efficacy and versatility. Common types of HA fillers include Restylane, Juvéderm, and Bolotero. Other various options available for HA fillers include the resilient HA fillers (RHA) collection, Revanesse versa, and Prevelle silk. The fillers can be used singularly or in combination to achieve a desired cosmetic outcome. The RHA collection line is the first FDA approved filler used to treat dynamic facial lines using a less rigid formula than earlier HA fillers and by uniquely adapting to facial movement, stretching, and repeated facial compression. Revanesse versa filler is designed to effectively address moderate to severe facial wrinkles, including nasolabial folds, with a focus on providing lasting results even after the HA filler has been absorbed. Other HA fillers such as Prevelle silk, Hydrelle, and Puragen contain 0.3% lidocaine for more tolerable treatment for moderate to severe facial lines. Examples of combination fillers include HA/botulinum toxin, HA/calcium hydroxyapatite (CaHA), and HA/poly‐ l‐lactic acid. To facilitate the administration of injections, HA fillers can also be mixed with agents such as lidocaine, lidocaine and epinephrine, normal saline, and sterile water to decrease viscosity. Furthermore, the use of CaHA in conjunction with microfocused ultrasound with visualization (MFU‐V) has shown to enhance skin tightness and neocollagenesis. Other applications of HA include utilization of its bacteriostatic effects to coat biomedical devices, as a material for bioink and tissue‐engineering, and to create novel formulations to further personalize cosmetic goals.

Between Beauty and the Law: Analyzing Cosmetic Filler Litigations in South Korea for Safer Medical Practices

“…A significant aspect of our findings is the predominance of complications related to Hyaluronic Acid (HA) fillers over other types. HA fillers have gained popularity in South Korea due to their perceived safety, versatility, and reversibility 16 . The ability to dissolve HA fillers using hyaluronidase in case of adverse events has contributed to their widespread use 17 .…”

“…The hydrophilic nature of HA allows the filler to integrate seamlessly with the surrounding tissues, creating a smooth and cohesive appearance 4 . This property also helps to maintain skin hydration and promote a more youthful and supple look 16 .…”

“…Another advantage of HA fillers is their versatility in treating a wide range of facial concerns 16 . From fine lines and wrinkles to deep folds and volume loss, HA fillers can be used to address multiple signs of aging in a single session 20 .…”

Legal analysis of South Korean cosmetic filler litigations for safer medical practices

“…A significant aspect of our findings is the predominance of complications related to Hyaluronic Acid (HA) fillers over other types. HA fillers have gained popularity in South Korea due to their perceived safety, versatility, and reversibility 16 . The ability to dissolve HA fillers using hyaluronidase in case of adverse events has contributed to their widespread use 17 .…”

“…The hydrophilic nature of HA allows the filler to integrate seamlessly with the surrounding tissues, creating a smooth and cohesive appearance 4 . This property also helps to maintain skin hydration and promote a more youthful and supple look 16 .…”