Other Modes of Detection

A detector is considered one of the most important components of LC and regarded as an input transducer which translates the changes in the chemical composition of the column effluents into electrical signals. The UV‐Visible absorbance detector, fluorescence detector, refractive index (RI) detector, conductivity detector, and mass detectors are most successful. Refractive index is a property of both the solute and the mobile phase. Alternatively, the detectors such as UV‐Vis and electrochemical based on the property of a solute but not solvent are called solute property detectors. The RI detector is widely used in exclusion chromatography but is less sensitive compared to UV. The chapter also overviews the photodiode array detector (PDA), electrochemical detector (ECD), carona charged aerosol detection (CAD), and conductivity detector. The important characteristics required for an ideal detector include sensitivity, linearity, universal or selectivity, low dead volume, and nondestructive.

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Other Modes of Detection

Cited by 2 publications

References 212 publications

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