Other primary headaches: Distinct clinical features and uncertain pathophysiology

Lee, Mi Ji; Peng, Kuan‐Po

doi:10.1177/03331024221147870

Cited by 3 publications

(2 citation statements)

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“…1 The association between headaches and various biochemical markers has been studied extensively, and recent research has suggested that there may be a significant association between the presence of headache and glucose profiles, total cholesterol in serum, HDL, and LDL. 12 This observation was supported by a study conducted by Rist et al 32 , found a strong association between increasing of total cholesterol and migraine, with odds ratio (95% confidence interval) was 4.67 (0.99-21.97). The authors also found strong associations between triglycerides and migraine (odds ratio 4.42 (1.32-14.77).…”

Section: Discussionmentioning

confidence: 63%

“…[9][10][11] The pathophysiology of migraines is complex and includes various factors such as genetics, environmental triggers, and lifestyle factors. [12][13][14] Vitamin D is essential for maintaining bone health 15 , regulating the immune system 7 , and maintaining a healthy. 16 Low levels of vitamin D have been shown to increase the risk of various health conditions, including metabolic disorders, autoimmune diseases, and cardiovascular diseases 17,18 .…”

Section: Introductionmentioning

confidence: 99%

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Association of altered serum glucose and lipid profiles with headaches in young women: clinical, cross-sectional study

Zola,

Da Silva,

Lima Filho

et al. 2023

Headache Med

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IntroductionHeadaches, including migraines and tension headaches, affect millions of people globally. Migraines are the most common neurological disorder, with around 14.4% of the world's population affected. It is suggested that dysregulation of biochemical markers and individual metabolic differences may contribute to headaches.ObjectiveWe evaluated the frequency of headaches or migraines with changes in lipid, glucose and vitamin D serum levels in young women.MethodsClinical, cross-sectional study with 139 young women, aged at least 18 years, based on the third edition of the International Classification of Headache Disorders (ICHD-3). The individuals were divided into two groups: one without headache and another with headache. Anthropometric analyzes (BMI, WC, BP and DBP) and blood samples were collected for analysis of vitamin D, glycemia and lipid profile.ResultsMean age was 22 (±4.6) years. We observed associations between headache and the following factors: high glucose levels (97 mg/dL, p=0.028), total cholesterol (180.4 mg/dL, p=0.002), HDL (44.2 mg/dL, p=0.017), and LDL (121.6 mg/dL, p=0.005). Longer duration of headache attacks was associated with increased levels of glucose (97.9 mg/dL, p=0.028), total cholesterol (186.8 mg/dL, p=0.05), diastolic blood pressure (74 mmHg, p=0.038), and BMI (24.6 kg/m2, p=0.024). High glucose levels were found to be directly related to the presence of migraine, particularly those with aura (105 mg/dL, p=0.034). However, there was no significant difference in vitamin D levels (p=0.640). ConclusionElevated levels of blood glucose and total plasma cholesterol and its fractions seems to be associated can increase with bouts of headache attacks, especially migraine, prolonging the duration of pain.

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Section: Discussionmentioning

confidence: 63%