Otoscopic diagnosis of middle ear effusion in acute and non-acute otitis media. I. The value of different otoscopic findings

Karma, Pekka; Penttilä, Matti; Sipilä, Markku; Kataja, Matti

doi:10.1016/0165-5876(89)90292-9

Cited by 124 publications

(81 citation statements)

References 9 publications

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“…When a non-suppurative effusion is present, it varies quantitatively and qualitatively. Smallvolume, clinically unapparent effusions may be found at tympanocentesis [Paradise et al, 1976;Orchik et al, 1978;Fiellau-Nikolajsen, 1983;Karma et al, 1989;Toner and Mains, 1990;Babonis et al, 1991;Finitzo et al, 1992;Ovesen et al, 1993;Sassen et al, 1994;van Balen and de Melker, 1994;Watters et al, 1997]. In OME, effusions may be serous or mucoid [Carrie et al, 1992]; the former are mucin poor and associated with less inflammation in terms of immunoglobulin and cytokine levels [Chung et al, 2002;Yabe et al, 2008] and leucocyte infiltration [Tanaka et al, 1986;Yoon et al, 1990] (and are more often of shorter duration [Yoon et al, 1990], unilateral, and in an older age group [Giebink et al, 1982a, b]).…”

Section: Pathological Analysesmentioning

confidence: 99%

“…In AOM, no single symptom [Hayden and Schwartz, 1985;Niemela et al, 1994;Medellin et al, 1996], group of symptoms [Niemela et al, 1994;Heikkinen and Ruuskanen, 1995] or sign on otoscopy [Karma et al, 1989] reliably predicts presence of middle ear effusion [Coker et al, 2010]. In OME, clinical tests for effusion are inaccurate [Zielhuis et al, 1990a, b;Takata et al, 2003].…”

Section: Pathological Analysesmentioning

confidence: 99%

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Epidemiology and Pathogenesis of Otitis Media: Construction of a Phenotype Landscape

Bhutta¹

2014

Audiol Neurotol

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Otitis media (OM) represents a complex set of clinically defined disease phenotypes. Epidemiological and pathological data suggest that inflammation of the middle ear occurs on a continuum of disease. Here I review epidemiological data and apply mathematical modelling to better define the interrelation of OM phenotypes, including the relationship of upper respiratory tract infection to acute OM (AOM), of AOM to OM with effusion, and of recurrent OM to chronicity of effusion. I use these mathematical models to represent OM graphically as a ‘landscape of disease'. This novel nosology may enable clinicians and researchers to better conceptualise middle ear inflammation in its various forms, although the limits of its application are also discussed.

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Section: Pathological Analysesmentioning

confidence: 99%

Section: Pathological Analysesmentioning

confidence: 99%

Epidemiology and Pathogenesis of Otitis Media: Construction of a Phenotype Landscape

Bhutta¹

2014

Audiol Neurotol

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“…10,11 If the tympanic membrane was perforated, the purulent discharge should be collected and analyzed. Culture and sensitivity help in diagnosis of the causative organism and guiding the choice of antibacterial agents.…”

Section: Diagnostic Approachmentioning

confidence: 99%

Otitis media among elderly: incidence, complication and prevention

Al-Sadeeq

Algarni

Alobaid

et al. 2018

Int J Community Med Public Health

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Though often considered a disease of children, otitis media can affect the elderly. The incidence of otitis media among elderly population is variable among countries, but generally low, with a value ranging from 0.25-9%. However, dangerous complications may occur. Otitis media is a complex spectrum of diseases that include acute otitis media, otitis media with effusion, suppurative otitis media, and mastoiditis. Otitis media in elderly doesn’t feature the classical presentation in children. Elderly patients experience otalgia with or without hearing loss or signs of inflammation. Infection may spread to either to adjacent structures leading to mastoiditis, petrositis, labyrinthitis, or facial nerve palsy, or intracranially leading to meningitis, subarachnoid abscess, subdural abscess, encephalitis, brain abscess, lateral or sigmoid venous sinus thrombosis, and otitis hydrocephalus. The mainstay strategies for prevention of otitis media are the adequate proper treatment of each infection, and tight control of modifiable risk factors such as tobacco smoking, immunosuppression, upper respiratory tract infection, allergy, and craniofacial abnormalities. Antimicrobial treatment should be continued for at least 10-14 years.

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“…4 The tympanic membrane is often cloudy with distinctly impaired mobility. 5 The air-fluid level or bubble may be visible in the middle ear.…”

Section: Introductionmentioning

confidence: 99%

A study on otitis media with special emphasis on acute suppurative otitis media

et al. 2014

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Otoscopic diagnosis of middle ear effusion in acute and non-acute otitis media. I. The value of different otoscopic findings

Cited by 124 publications

References 9 publications

Epidemiology and Pathogenesis of Otitis Media: Construction of a Phenotype Landscape

Epidemiology and Pathogenesis of Otitis Media: Construction of a Phenotype Landscape

Otitis media among elderly: incidence, complication and prevention

A study on otitis media with special emphasis on acute suppurative otitis media

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