Otosyphilis: A review of 85 cases

Yimtae, Kwanchanok; Srirompotong, Somchai; Lertsukprasert, Krisna

doi:10.1016/j.otohns.2006.08.026

Cited by 77 publications

(50 citation statements)

References 12 publications

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“…21 These are typically acute meningitis (headache, neck stiffness, photophobia, nausea) and cranial nerve palsies including eighth nerve palsy with resultant hearing loss and possible tinnitus. 29 Eye involvement may result in uveitis (most commonly posterior), optic neuropathy, interstitial keratitis and retinal involvement. 30 Latent disease…”

Section: Acquired (Adult) Diseasementioning

confidence: 99%

UK national guidelines on the management of syphilis 2015

Kingston¹,

et al. 2015

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These guidelines are an update for 2015 of the 2008 UK guidelines for the management of syphilis. The writing group have piloted the new BASHH guideline methodology, notably using the GRADE system for assessing evidence and making recommendations. We have made significant changes to the recommendations for screening infants born to mothers with positive syphilis serology and to facilitate accurate and timely communication between the teams caring for mother and baby we have developed a birth plan. Procaine penicillin is now an alternative, not preferred treatment, for all stages of syphilis except neurosyphilis, but the length of treatment for this is shortened. Other changes are summarised at the start of the guideline.

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Section: Acquired (Adult) Diseasementioning

confidence: 99%

UK national guidelines on the management of syphilis 2015

Kingston¹,

et al. 2015

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“…A few reports have shown that hearing can potentially recover following therapy for a few conditions, including vestibular schwannoma, mumps, and secondary syphilis (Berg et al, 1986;Jeans, Wilkins, & Bonington, 2008;Vuori et al, 1962). Unfortunately, disease-specific therapy treatment does not improve hearing to preonset levels in the majority of SSNHL cases of identifiable etiology (Garcia Berrocal et al, 1999;Lorenzi et al, 2003;Nosrati-Zarenoe et al, 2010;Yimtae et al, 2007).…”

Section: Treatmentmentioning

confidence: 99%

“…In many such cases, hearing will not improve following appropriate therapy for the underlying pathologic process (Garcia Berrocal et al, 1999;Lorenzi et al, 2003;Nosrati-Zarenoe et al, 2010;Yimtae et al, 2007).…”

Section: Prognosismentioning

confidence: 99%

Sudden Sensorineural Hearing Loss

Kuhn

Heman‐Ackah

Shaikh

et al. 2011

Trends in Amplification

382

190

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Sudden sensorineural hearing loss (SSNHL) is commonly encountered in audiologic and otolaryngologic practice. SSNHL is most commonly defined as sensorineural hearing loss of 30dB or greater over at least three contiguous audiometric frequencies occurring within a 72-hr period. Although the differential for SSNHL is vast, for the majority of patients an etiologic factor is not identified. Treatment for SSNHL of known etiology is directed toward that agent, with poor hearing outcomes characteristic for discoverable etiologies that cause inner ear hair cell loss. Steroid therapy is the current mainstay of treatment of idiopathic SSNHL in the United States. The prognosis for hearing recovery for idiopathic SSNHL is dependent on a number of factors including the severity of hearing loss, age, presence of vertigo, and shape of the audiogram.

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“…In this study treatment resulted in improvement of hearing in 93% of cases in the short term and 91% in the long term. 8 Otosyphilis is an important and potentially reversible cause of deafness. We also point out that Maria Hadjivassiliou's name should be spelt as is given here.…”

Section: Discussionmentioning

confidence: 99%

Syphilis causing hearing loss

Chan

Medhi²,

Ekbote³

et al. 2008

Int J STD AIDS

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An HIV-positive man with hepatitis B co-infection, naïve to highly active antiretroviral therapy, with a CD4 of 594 copies/mL and HIV-1 viral load of 140,070 copies, presented with right-sided facial weakness and hearing loss. He had been treated for secondary syphilis three months earlier when his rapid plasma reagin (RPR) result was 1:16, this had fallen to neat. At presentation, his RPR had risen to 1:16 again. A magnetic resonance imaging scan showed enhancement of the internal auditory canal and right cochlea. His cerebrospinal fluid examination was normal. He was treated with acyclovir and prednisolone before the syphilis serology was known. He was then treated for syphilis with doxycycline. He made an excellent recovery.

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Otosyphilis: A review of 85 cases

Abstract: Further study about hearing outcomes among treatment modalities is suggested.

Cited by 77 publications

References 12 publications

UK national guidelines on the management of syphilis 2015

UK national guidelines on the management of syphilis 2015

Sudden Sensorineural Hearing Loss

Syphilis causing hearing loss

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