Objective
To explore whether MRI fusion technology (combined T2-weighted imaging [T2WI] and fat-suppressed T2WI [T2WI-
FS
]) improves signal differences between anal fistulas and surrounding structures.
Materials and Methods
A total of 32 patients with confirmed diagnoses of anal fistula were retrospectively studied. All available T2WI and T2WI-
FS
images for each patient were used to generate fusion image (T2WI-
Fusion
) based on the addition of gray values obtained from each pixel via an MR post-processing work station. The discriminability of fistula, perianal sphincter, and perianal fat in T2WI, T2WI-
FS
, and T2WI-
Fusion
images was quantified with Fisher's scoring algorithm. For subjective visual image assessment by researchers, five-point scale scores were determined using a modified double-stimulus continuous quality-scale test to evaluate T2WI-
FS
, T2WI, enhanced axial three-dimensional-volumetric interpolated breath-hold examination (3D-VIBE), and T2WI-
Fusion
sequence images. The differences were subsequently compared.
Results
Mean Fisher scores for fistulas vs. sphincters obtained from T2WI-
Fusion
(F
Fusion-fistula
= 6.56) were significantly higher than those from T2WI (F
T2WI-fistula
= 3.35) (
p
= 0.001). Mean Fisher scores for sphincters vs. fat from T2WI-
Fusion
(F
Fusion-sphincter
= 10.84) were significantly higher than those from T2WI-
FS
(FS
FS-sphincter
= 2.57) (
p
= 0.001). In human assessment, T2WI-
Fusion
showed the same fistula discriminability as T2WI-
FS
, and better sphincter discriminability than T2WI. Overall, T2WI-
Fusion
showed better discriminability than T2WI, T2WI-
FS
, and enhanced 3D-VIBE images.
Conclusion
T2WI and T2WI-
FS
fusion technology improves signal differences between anal fistulas and surrounding structures, and may facilitate better evaluation of anal fistulas and sphincters.