Our surgical treatment results in pT3N0 laryngeal squamous cell carcinoma

Abstract

Objectives: This study aimed to evaluate the effect of surgical treatment on disease control, survival rates, and prognostic factors in patients with pT3N0 laryngeal squamous cell carcinoma. Patients and Methods: Files of pT3N0 laryngeal squamous cell carcinoma (LSCC) patients who were surgically treated between January 2009 and December 2019 were retrospectively screened. Forty-four patients (42 males, 2 females; mean age: 59.6±9.2 years; range, 44 to 86 years) diagnosed with pT3N0 LSCC who underwent total laryngectomy or partial laryngectomy as primary treatment were included in the study. Results: The mean follow-up period of the patients was 45.8±38.4 months. The tumor was supraglottic in 20 patients, glottic in 21 patients, and transglottic in three patients. Total laryngectomy was performed in 32 patients, and partial laryngectomy was performed in 12 patients. In five (11.3%) of the patients, recurrence occurred. There was no statistically significant link between recurrence and tumor location, surgical technique, or perineural or lymphovascular invasion. The five-year survival rate was 72.7%, with no differences in survival rates based on the type of surgery performed. Conclusion: Surgical treatment is a safe option for pT3N0 squamous cell carcinoma patients. In patients with appropriate criteria, partial laryngectomy has a similar success to total laryngectomy.