Our Timing to Remove Peritoneal Catheter Dialysis After Kidney Transplant

Peluso, G.; Incollingo, Paola; Carlomagno, Nicola; d’Alessandro, V.; Tammaro, Vincenzo; Caggiano, Marcello; Sotelo, M.L. Sandoval; Rupealta, Nicolò; Cândida, Maria; Mazzoni, G; Campanile, Silvia; Chiacchio, Gaetano; Scotti, Alessandro; Santangelo, Michele

doi:10.1016/j.transproceed.2018.04.075

Cited by 11 publications

(7 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Multiple studies have looked at the incidence of PDrelated side effects in the post-transplantation period. [18][19][20][21][22][23][24] Some have reported high incidence of complications such as peritonitis, wound infection, and 19,21 However, very few studies have compared the short-and long-term outcomes of patients undergoing PD versus HD during DGF. Thomson et al 29 compared the outcomes of 14 patients undergoing PD in DGF with those of 63 patients who underwent HD at two Canadian transplantation centers.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Continuation of Peritoneal Dialysis in Adult Kidney Transplant Recipients With Delayed Graft Function

Gardezi

Muth

Ghaffar

et al. 2021

Kidney International Reports

View full text Add to dashboard Cite

Introduction: Peritoneal dialysis (PD) has been used increasingly in past decade. Many of these patients undergo transplantation and may require dialysis for delayed graft function (DGF). The outcomes of DGF based on the post-transplantation dialysis modality are not well known. Methods:We retrospectively reviewed all adult kidney transplant recipients (KTRs) from the University of Wisconsin School of Medicine and Public Health who developed DGF between November 2015 and April 2019. Patients were divided into those who received hemodialysis (HD) or PD during the DGF period. Immediate graft explant, DGF among living donor KTRs, or those requiring just a single dialysis treatment were excluded.Results: Of 224 KTRs with DGF during the study period, 167 fulfilled our selection criteria. There were 16 patients in the PD and 151 in the HD group. Baseline characteristics were similar between the two groups, except diabetes was more prevalent in the HD group. Five of 16 PD patients had to be transitioned to HD. There was no difference in DGF duration, hospital length of stay, infectious or surgical complications, rejection at various time periods, graft function at last follow-up, or graft failure. In multivariate analysis, only rejection within the first year of transplantation (hazard ratio [HR]: 4.26; 95% confidence interval [CI]: 1.20-15.08; P ¼ 0.02) and post-surgical complications (HR: 3.79; 95% CI: 1.03-13.91; P ¼ 0.04) were associated with death-censored graft failure (DCGF). The use of PD for treatment of DGF was not associated with DCGF.Conclusions: In carefully selected patients, PD can be continued safely for DGF without any effect on shortterm or long-term transplant outcomes.

show abstract

Section: Discussionmentioning

confidence: 99%

“…[18][19][20][21] On the other hand, some studies have shown a low rate of these complications. [22][23][24] Consequently, there is no consensus on how long the PD catheter should be retained after transplantation and whether PD should be performed in DGF. 25 In 2015, our program implemented guidelines to continue PD in patients who developed DGF.…”

mentioning

confidence: 99%

Continuation of Peritoneal Dialysis in Adult Kidney Transplant Recipients With Delayed Graft Function

Gardezi

Muth

Ghaffar

et al. 2021

Kidney International Reports

View full text Add to dashboard Cite

show abstract

“…All the data show the need to reduce the immunosuppression therapy in symptomatic and asymptomatic patients [ 5 , 20 – 23 ]. As we did not have any infected patient at the moment, we have administered the usual immunosuppressive therapy, at the minimum effective doses [ 24 ].…”

Section: Discussionmentioning

confidence: 99%

[Retracted] COVID‐19 and Living Donor Kidney Transplantation in Naples during the Pandemic

Peluso

Campanile

Scotti

et al. 2020

BioMed Research International

View full text Add to dashboard Cite

Introduction. SARS-CoV-2 is a virus that causes a potentially deadly syndrome that affects especially the respiratory tract. Kidney-transplanted patients are immunosuppressed and more susceptible to viral infections. We have examined our transplantation activity to explore the future role of kidney transplantation from deceased and living donors in COVID-19 era. Patients and Methods. The activity of our transplant center of Naples (one of the two transplant centers in Campania, South Italy) continued during the COVID-19 pandemic. We have analysed the kidney transplants carried out between March 9 and June 9, 2020, comparing these data with the numbers of procedures performed in the two previous years. Moreover, we have considered the possibility of performing living donor transplants during a worldwide pandemic. Results. From March 9, 2020, when the Italian lockdown begun, till June 9, 2020, five kidney transplants have been performed at our transplant center in Naples, all from deceased donors. The donors and the recipients have been screened for COVID-19 infection, and the patients, all asymptomatic, followed strict preventive measures and were fully informed about the risks of surgery and immunosuppression during a pandemic. All the transplanted patients remained COVID negative during the follow-up. The number of transplants performed has been constant compared to the same months of 2018 and 2019. In agreement with the patients, we decided to postpone living donor transplants to a period of greater control of the SARS-CoV-2 spread in Italy. Conclusion. Deceased donor kidney transplantation should continue, especially in a region with moderate risk, like Campania, with a more careful selection of donors and recipients, preferring standard donors and recipients without severe comorbidities. Living donor transplantation program, instead, should be postponed to a period of greater control of the SARS-CoV-2 spread, as it is an elective surgery and its delay does not determine additional risks for patients.

show abstract

“…The lack of evidence-based guidelines leads to the presence of varying policies adopted by different centers and specialists. Some routinely leave the catheters in situ [4,5,[36][37][38][39][40] while others remove them as a rule during the transplant procedure [6,7]. There are certain situations when indwelling peritoneal catheters should be removed before or at the time of kidney implantation, including infectious (peritonitis, exit-site/tunnel/inner cuff infection), non-infectious and mechanical (broken catheter, catheter migration, pericatheter leak, flow dysfunction, peritoneal loss of function, peritoneal membrane breach, pleuri-peritoneal communication, sclerosant peritonitis), and some rare complications (allergic reaction, organ erosion, severe infusion/pressure pain, hemoperitoneum) [41,42].…”

Section: Discussionmentioning

confidence: 99%

Peritoneal dialysis catheter removal at the time or after kidney transplantation: a systematic review and meta-analysis

Zawistowski

Nowaczyk

Domagała

2022

Langenbecks Arch Surg

View full text Add to dashboard Cite

Purpose An increasing number of patients treated with peritoneal dialysis eventually undergo kidney transplantation. Owing to opposing reports, we aimed to find evidence about the best time for peritoneal dialysis catheter removal in transplant patients. Methods We conducted a systematic review and random effects meta-analysis of non-randomized studies of intervention comparing patients with peritoneal dialysis catheters left in place or removed during kidney transplantation in regard to the need for dialysis and occurrence of catheter-related complications. We searched (last update on 8 December 2021) PubMed, Embase, Scopus, and Web of Science for eligible studies. ROBINS-I tool and funnel plot asymmetry analysis were used to assess the quality of included articles. Results Eight observational studies were evaluated. Five of them, which involved 338 patients, were included in a meta-analysis. All were at moderate to serious risk of bias. The odds of needing dialysis are more than twice as high for patients with peritoneal dialysis catheters left in situ (pooled odds ratio, 2.21; 95% confidence interval [CI], 1.03 to 4.73; I2 = 0%). No statistically significant difference was noted when adult and pediatric subgroups were compared (Q = 0.13, P = .720). More individuals with catheters left in place required dialysis (pooled prevalence, 20.9%; 95% CI, 13.6 to 30.7%; I2 = 59% vs. 12.4%; 95% CI, 5.6 to 25.2%; I2 = 0%) and experienced catheter-related infections. Conclusion Available evidence is scarce. Unless new data from a randomized controlled trial are available, the dilemma of peritoneal dialysis catheter removal cannot be solved. Trial registration PROSPERO Protocol ID: CRD42020207707. Graphical abstract

show abstract

Our Timing to Remove Peritoneal Catheter Dialysis After Kidney Transplant

Cited by 11 publications

References 32 publications

Continuation of Peritoneal Dialysis in Adult Kidney Transplant Recipients With Delayed Graft Function

Continuation of Peritoneal Dialysis in Adult Kidney Transplant Recipients With Delayed Graft Function

[Retracted] COVID‐19 and Living Donor Kidney Transplantation in Naples during the Pandemic

Peritoneal dialysis catheter removal at the time or after kidney transplantation: a systematic review and meta-analysis

Contact Info

Product

Resources

About