We systematically study quantum effect on chiral and U A ð1Þ symmetry breaking under external electromagnetic fields in the frame of equal-time Wigner function formalism. We derive the transport and constraint equations for the quark distribution functions and the chiral and pion condensates in a Nambu-Jona-Lasinio model. By taking semiclassical expansion of the equations, chiral symmetry is broken at classical level, while U A ð1Þ symmetry breaking happens only at quantum level. Beyond quasiparticle approximation, the quark off-shell effect leads to strong oscillation for the chiral and pion condensates. DOI: 10.1103/PhysRevD.98.016007 In the chiral limit with zero current quark mass, the Lagrangian density of the quantum chromodynamics (QCD) respects the symmetry of U L ð3Þ × U R ð3Þ ¼ U V ð1Þ× U A ð1Þ × SU L ð3Þ × SU R ð3Þ at classical level. However, the quark-antiquark condensate hψψi spontaneously breaks the SU L ð3Þ × SU R ð3Þ symmetry, and the U A ð1Þ symmetry is broken by the quantum anomaly due to the nontrivial topology of the principal bundle of gauge field [1,2]. Chiral symmetry breaking leads to a rich meson and baryon spectrum, and as a supplement the U A ð1Þ anomaly explains the nondegeneracy of η and η 0 mesons [3][4][5]. Like temperature and chemical potential, strong electromagnetic fields provide another way to change the QCD symmetries. For chiral symmetry, lattice simulations and effective model calculations show that, the magnetic field enhances the chiral symmetry breaking in vacuum which is called magnetic catalysis but reduces the critical temperature of the symmetry restoration which is called inverse magnetic catalysis [6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21]. As a gauge field, the parallel electromagnetic fields can also break down the U A ð1Þ symmetry [22,23], characterized by the pseudoscalar condensate hψiγ 5 τ 3 ψi via the electromagnetic triangle anomaly process π 0 → 2γ.In laboratories, the electromagnetic fields which are strong enough to modify the QCD properties can be formed only in the beginning of high energy nuclear collisions [24][25][26]. Since the fields are created by the spectators of the collisions, they can be considered as external or classical fields for the parton motion in the fireball. Considering that the parton system in the initial stage is in nonequilibrium state, the interaction between the partons and the electromagnetic fields should be described in the frame of a kinetic theory. Recently, a quantum kinetic equation to describe the chiral fermion motion in electromagnetic fields is developed via different methods and applied to heavy ion collisions [27][28][29][30][31]. In this paper, we study the out-ofequilibrium U A ð1Þ symmetry breaking in electromagnetic fields and its relation to the chiral symmetry breaking in the frame of Wigner function formalism [32][33][34][35].We effectively describe the quantum anomaly induced U A ð1Þ symmetry breaking and spontaneous chiral symmetry breaking in a Nambu-Jona-Lasinio (NJL) model [36] ...