Out-of-hospital ventricular fibrillation in patients with acute myocardial infarction

Gheeraert, Peter; Henriques, José P.S.; Buyzere, Marc L. De; Voet, Joeri; Calle, Pol; Taeymans, Yves; Zijlstra, Felix

doi:10.1016/s0735-1097(99)00490-8

Cited by 55 publications

(41 citation statements)

References 23 publications

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“…Infarct location and culprit coronary artery were not identified as independent, significant risk factors. Recently, Gheeraert et al 7 showed that an occlusion of the left coronary artery (left anterior descending coronary artery and right circumflex artery) was associated with a greater risk of VF than an occlusion of the right coronary artery. Probably, differences in inclusion criteria and smaller sample size in the latter study explain these differences.…”

Section: Discussionmentioning

confidence: 99%

“…6 A large ischemic area is not associated with an increased probability of VF. 7 Site of infarction has been reported as a potential risk factor, because 2 relatively small studies showed that anterior myocardial wall infarction was more prevalent among primary VF patients than acute myocardial infarction patients without VF. 7,8 Two important epidemiological studies introduced the concept of a genetic risk factor for SCD.…”

Section: Editorial P 1134 Clinical Perspective P 1145mentioning

confidence: 99%

“…7 Site of infarction has been reported as a potential risk factor, because 2 relatively small studies showed that anterior myocardial wall infarction was more prevalent among primary VF patients than acute myocardial infarction patients without VF. 7,8 Two important epidemiological studies introduced the concept of a genetic risk factor for SCD. In a populationbased case-control study, a family history of myocardial infarction or SCD was, after correction for all common risk factors, positively associated with the risk of SCD.…”

Section: Editorial P 1134 Clinical Perspective P 1145mentioning

confidence: 99%

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Familial Sudden Death Is an Important Risk Factor for Primary Ventricular Fibrillation

et al. 2006

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Background-Primary ventricular fibrillation (VF) accounts for the majority of deaths during the acute phase of myocardial infarction. Identification of patients at risk for primary VF remains very poor. Methods and Results-We performed a case-control study in patients with a first ST-elevation myocardial infarction (STEMI) to identify independent risk factors for primary VF. A total of 330 primary VF survivors (cases) and 372 controls were included; patients with earlier infarcts or signs of structural heart disease were excluded. Baseline characteristics, including age, gender, drug use, and ECG parameters registered well before the index infarction, as well as medical history, were not different. Infarct size and location, culprit coronary artery, and presence of multivessel disease were similar between groups. Analysis of ECGs performed at hospital admission for the index STEMI revealed that cumulative ST deviation was significantly higher among cases (OR per 10-mm ST deviation 1.59, 95% CI 1.25 to 2.02). Analysis of medical histories among parents and siblings showed that the prevalence of cardiovascular disease was similar between cases and controls (73.1% and 73.0%, respectively); however, familial sudden death occurred significantly more frequently among cases than controls (43.1% and 25.1%, respectively; OR 2.72, 95% CI 1.84 to 4.03). Conclusions-In a population of STEMI patients, the risk of primary VF is determined by cumulative ST deviation and family history of sudden death.

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Section: Discussionmentioning

confidence: 99%

Section: Editorial P 1134 Clinical Perspective P 1145mentioning

confidence: 99%

Section: Editorial P 1134 Clinical Perspective P 1145mentioning

confidence: 99%

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Familial Sudden Death Is an Important Risk Factor for Primary Ventricular Fibrillation

et al. 2006

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“…A lesion was considered the culprit if it appeared fresh on angiography and, in case of more than one lesion, if it corresponded with the location of ST elevation on the electrocardiogram. 11 Echocardiography data were gathered retrospectively. Medication use during follow-up was gathered by a written 1-year follow-up questionnaire to all PCI patients in the Academic Medical Center, Amsterdam, The Netherlands, which accounted for most of the included patients.…”

Section: Data Collectionmentioning

confidence: 99%

Prognosis among survivors of primary ventricular fibrillation in the percutaneous coronary intervention era

Jong

Marsman

Henriques

et al. 2009

American Heart Journal

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“…However, the AMI mortality rate is highest during patient transfer to hospital following symptom onset, and the major cause of death is ventricular fibrillation resulting from occlusion of the IRA. 35 Thus, early reperfusion soon after symptom onset is important to reduce overall AMI mortality. In terms of prehospital thrombolysis, 36 cooperation between clinics and hospitals makes it possible to provide medical care before arriving at hospital and to reduce cardiac dysfunction and subsequently improve prognosis in the chronic phase, resulting in good quality of life.…”

Section: Discussionmentioning

confidence: 99%

Increasingly Well-Preserved Left Ventricular Function in Hospital Survivors With Acute Myocardial Infarction Effect of Early and Complete Reperfusion Strategy on Left Ventricular Remodeling

Tani

Nagao

Watanabe

et al. 2007

Circ J

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rogress in reperfusion therapy for acute myocardial infarction (AMI) has greatly reduced mortality in the acute phase, which is when most deaths associated with AMI occur. [1][2][3][4] Reperfusion therapy is classified as either thrombolytic therapy, which is easy to perform and promptly achieves Thrombolysis In Myocardial Infarction (TIMI) grade 3 flow (TIMI-3 flow), or percutaneous coronary intervention (PCI), which has a higher reperfusion rate. The advantages and disadvantages of the 2 therapies have long been controversial; [5][6][7] however, the accumulation of data from recent large-scale randomized controlled trials has provided evidence-based information on reperfusion therapy, [8][9][10][11] leading to increasing awareness of the importance of starting reperfusion therapy as early as possible after the onset of AMI, regardless of the modality, in order to achieve earlier and complete revascularization of infarctrelated arteries (IRAs) and to maintain revascularization.As a result, a new treatment strategy needs to be developed.Against this backdrop, we have performed combination therapy (FAST therapy: Fibrinolytic And Subsequent Transluminal angioplasty 12 ) since 1997. It involves administering a thrombolytic agent as early as possible after the diagnosis of AMI, followed by PCI if TIMI-3 flow is not achieved. We have shown recently in the FAST trials that the shorter door-to-TIMI-3 time (time interval from arrival at the emergency room until the patient achieves TIMI-3 flow), the more left ventricular (LV) remodeling is suppressed, which indicates that achieving and maintaining TIMI-3 flow early after AMI onset is crucial for myocardial protection. 13 The purpose of this study was to investigate how LV remodeling, a prognostic factor in hospital survivors with myocardial infarction (MI), has changed with the changes in treatment, especially advancements in coronary reperfusion therapy, during the 14-year period from 1989 to 2002.We re-examined the relationship between the factors affecting reperfusion, including the door-to-TIMI-3 time, and LV remodeling and discuss the significance of reperfusion therapy for AMI. Methods SubjectsFor this study, we selected 813 patients with a first diag- Background Progress in reperfusion therapy for acute myocardial infarction (AMI) has greatly reduced acute phase mortality, but few data exist regarding the time trends in left ventricular (LV) remodeling in hospital survivors of AMI. Methods and ResultsThe study enrolled 813 patients with AMI who had received reperfusion therapy and survived to hospital discharge. The patients were divided into chronological groups: first treatment received between 1989 and 1992, n=196; 1993 and 1995, n=193; 1996 and 1998, n=211; and 1999 and 2002, n=213. A comparison was made of LV ejection fraction (LVEF) and LV end-diastolic volume index (LVEDVI) at 6 months after symptom onset. Along with the temporal improvements reperfusion therapy, LVEF and LVEDVI improved over time (55±14, 58±13, 59±13, 61±13%, p<0.001; 98±30, 94±27, 90±31,...

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Out-of-hospital ventricular fibrillation in patients with acute myocardial infarction

Cited by 55 publications

References 23 publications

Familial Sudden Death Is an Important Risk Factor for Primary Ventricular Fibrillation

Familial Sudden Death Is an Important Risk Factor for Primary Ventricular Fibrillation

Prognosis among survivors of primary ventricular fibrillation in the percutaneous coronary intervention era

Increasingly Well-Preserved Left Ventricular Function in Hospital Survivors With Acute Myocardial Infarction Effect of Early and Complete Reperfusion Strategy on Left Ventricular Remodeling

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