Outbreak of nosocomial urinary tract infections caused by Serratia marcescens

Abstract

of nosocomial urinary tract infections appeared to be due to strains of Serratia marcescens that were resistant to currently available antibiotics. The serotyping and antibiotic susceptibility patterns suggested a few endemic strains of serotypes 013, 02/3, 012/14, and nontypable strains. These strains were isolated from the urine samples of inpatients with urinary tract infections in the urology ward and in other wards. The strains of 012/14 (gentamicin susceptible) were replaced with those of 02/3 (gentamicin resistant) between June and September 1981, whereas the other serotypes were isolated continuously. They were resistant to sulbenicillin, cefmetazole, gentamicin, and amikacin, and susceptible to micronomicin and ofloxacin, a new quinolone antibiotic. Most of them were also resistant to the disinfectant chlorhexidine, which had been used widely for hand washing in the hospital.

Effects of temperature, nutrients, organic matter and coral mucus on the survival of the coral pathogen, Serratia marcescens PDL100

“…While much is known about S. marcescens in clinical settings (e.g. Davis et al, 1970;Hamilton and Brown, 1972;Okuda et al, 1984;Miranda et al, 1996;Carbonell et al, 2000), relatively little is known about this bacterium in the marine environment. The coral-pathogenic strain PDL100 has been proven to infect tissues of A. palmata (Patterson et al, 2002), but it is not clear if this strain has adapted to a marine existence (i.e.…”

Epidemiologic Background of Hand Hygiene and Evaluation of the Most Important Agents for Scrubs and Rubs

“…It may also be explained by the presence of plasmids which code for chlorhexidine resistance (269) and may therefore be transfered to other bacterial species (486,619). A change in lipid content or a reduced adsorption of the antiseptic can be excluded as the main mechanism of resistance, as shown with isolates from urinary tract infections caused by P. mirabilis (554) and S. marcescens (410).…”

Phytosynthesized silver nanoparticles as antiquorum sensing and antibiofilm agent against the nosocomial pathogenSerratia marcescens: anin vitrostudy

“…There are many Gram-negative and Gram-positive bacteria that secrete acyl homoserine lactones (AHLs) and oligopeptides as their AIs, respectively (Miller and Bassler 2001). Among the numerous bacteria that communicate through QS systems, Serratia marcescens is one of the important human pathogens responsible for frequent hospitalacquired infections including urinary tract infections (UTI) (Okuda et al 1984), respiratory tract infections (Vigeant et al 1998), pneumonia (Jones 2010), meningitis (Zaidi et al 1989), conjunctivitis (McNaughton et al 1995), osteomyelitis (Martins et al 2015), endocarditis (Korner et al 1994) and bloodstream infections (Iosifidis et al 2012).…”